PMID- 20554605
OWN - NLM
STAT- MEDLINE
DCOM- 20101207
LR  - 20211020
IS  - 1552-5783 (Electronic)
IS  - 0146-0404 (Print)
IS  - 0146-0404 (Linking)
VI  - 51
IP  - 11
DP  - 2010 Nov
TI  - Retinal structure of birds of prey revealed by ultra-high resolution 
      spectral-domain optical coherence tomography.
PG  - 5789-95
LID - 10.1167/iovs.10-5633 [doi]
AB  - PURPOSE: To reveal three-dimensional (3-D) information about the retinal 
      structures of birds of prey in vivo. METHODS: An ultra-high resolution 
      spectral-domain optical coherence tomography (SD-OCT) system was built for in 
      vivo imaging of retinas of birds of prey. The calibrated imaging depth and axial 
      resolution of the system were 3.1 mm and 2.8 mum (in tissue), respectively. 3-D 
      segmentation was performed for calculation of the retinal nerve fiber layer 
      (RNFL) map. RESULTS: High-resolution OCT images were obtained of the retinas of 
      four species of birds of prey: two diurnal hawks (Buteo platypterus and Buteo 
      brachyurus) and two nocturnal owls (Bubo virginianus and Strix varia). These 
      images showed the detailed retinal anatomy, including the retinal layers and the 
      structure of the deep and shallow foveae. The calculated thickness map showed the 
      RNFL distribution. Traumatic injury to one bird's retina was also successfully 
      imaged. CONCLUSIONS: Ultra-high resolution SD-OCT provides unprecedented 
      high-quality 2-D and 3-D in vivo visualization of the retinal structures of birds 
      of prey. SD-OCT is a powerful imaging tool for vision research in birds of prey.
FAU - Ruggeri, Marco
AU  - Ruggeri M
AD  - Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 
      Miami, Florida, USA.
FAU - Major, James C Jr
AU  - Major JC Jr
FAU - McKeown, Craig
AU  - McKeown C
FAU - Knighton, Robert W
AU  - Knighton RW
FAU - Puliafito, Carmen A
AU  - Puliafito CA
FAU - Jiao, Shuliang
AU  - Jiao S
LA  - eng
GR  - R21 EB008800/EB/NIBIB NIH HHS/United States
GR  - P30 EY014801/EY/NEI NIH HHS/United States
GR  - R21 EB008800-01/EB/NIBIB NIH HHS/United States
GR  - 1R21 EB008800-01/EB/NIBIB NIH HHS/United States
GR  - R21 EB008800-03/EB/NIBIB NIH HHS/United States
GR  - P30EY014801/EY/NEI NIH HHS/United States
GR  - R21 EB008800-02/EB/NIBIB NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20100616
PL  - United States
TA  - Invest Ophthalmol Vis Sci
JT  - Investigative ophthalmology & visual science
JID - 7703701
SB  - IM
MH  - *Anatomy, Cross-Sectional
MH  - Animals
MH  - Hawks/*anatomy & histology
MH  - Imaging, Three-Dimensional
MH  - Retina/*anatomy & histology
MH  - Strigiformes/*anatomy & histology
MH  - *Tomography, Optical Coherence
PMC - PMC3061512
EDAT- 2010/06/18 06:00
MHDA- 2010/12/14 06:00
PMCR- 2011/05/01
CRDT- 2010/06/18 06:00
PHST- 2010/06/18 06:00 [entrez]
PHST- 2010/06/18 06:00 [pubmed]
PHST- 2010/12/14 06:00 [medline]
PHST- 2011/05/01 00:00 [pmc-release]
AID - iovs.10-5633 [pii]
AID - 10-5633 [pii]
AID - 10.1167/iovs.10-5633 [doi]
PST - ppublish
SO  - Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5789-95. doi: 10.1167/iovs.10-5633. 
      Epub 2010 Jun 16.