PMID- 20560099
OWN - NLM
STAT- MEDLINE
DCOM- 20101012
LR  - 20100618
IS  - 1439-3999 (Electronic)
IS  - 0023-2165 (Linking)
VI  - 227
IP  - 6
DP  - 2010 Jun
TI  - [1-year results after posterior lamellar keratoplasty with manually dissected 
      donor tissue].
PG  - 460-6
LID - 10.1055/s-0029-1245475 [doi]
AB  - OBJECTIVE: Posterior lamellar keratoplasty (PLK) is a reasonable alternative to 
      penetrating keratoplasty (PK) for pathological changes of the corneal 
      endothelium. The lamellar preparation of the donor tissue can be done in an 
      automated fashion with a microkeratome, Descemet Stripping Automated Keratoplasty 
      (DSAEK) or manually, Descemet Stripping Endothelial Keratoplasty (DSEK). Here, we 
      describe our clinical results with one year follow-up using manually dissected 
      donor lamellae for PLK. METHODS: For 28 eyes (28 patients) best-corrected visual 
      acuity, corneal topography, esthesiometry, pachymetry, as well as endothelial 
      cell count were measured before, 1 day, 1 and 6 weeks, as well as 3, 6 and 12 
      months after surgery. RESULTS: 3 of 28 grafts showed primary graft failure. For 
      19 eyes (no other vision-limiting diseases), the best-corrected visual acuity 
      rose on average from 1.0 +/- 0.53 to 0.4 +/- 0.20 (logMAR) 1 year after surgery. 
      The surgically induced astigmatism changed from 3.8 +/- 2.8 dpt preoperatively to 
      1.4 +/- 1.0 dpt 12 months after DSEK. The pachymetry measured by slit lamp showed 
      an averaged thickness of 649 +/- 54 mm pre- and 776 +/- 75 mm one week and 636 
      +/- 79 mm 1 year after surgery was performed. The endothelial cell count of the 
      grafts was 2615 +/- 156 cells/mm (2), after one year postoperatively the mean 
      endothelial cell count was 2084 +/- 536 cells/mm (2). The esthesiometry showed a 
      slight rise from 0.96 +/- 0.34 g/mm (2) pre- to 0.96 +/- 0.03 g/mm (2) one year 
      post-surgery. CONCLUSIONS: The postoperative course of our patients shows that 
      improvement of visual acuity by PLK with manually dissected donor tissue is 
      possible.
CI  - Georg Thieme Verlag KG Stuttgart, New York.
FAU - Weller, K K
AU  - Weller KK
AD  - Klinik und Poliklinik fur Augenheilkunde, Julius-Maximilians-Universitat 
      Wurzburg, Wurzburg.
FAU - Unterlauft, J D
AU  - Unterlauft JD
FAU - Geerling, G
AU  - Geerling G
LA  - ger
PT  - Clinical Trial
PT  - English Abstract
PT  - Journal Article
TT  - 1-Jahres-Ergebnisse nach posteriorer lamellarer Keratoplastik mit manuell 
      disseziertem Spendermaterial.
DEP - 20100617
PL  - Germany
TA  - Klin Monbl Augenheilkd
JT  - Klinische Monatsblatter fur Augenheilkunde
JID - 0014133
SB  - IM
MH  - Aged
MH  - Corneal Transplantation/*methods
MH  - Dissection/*methods
MH  - Female
MH  - Humans
MH  - Male
MH  - *Tissue Donors
MH  - Treatment Outcome
MH  - Vision Disorders/*diagnosis/*surgery
EDAT- 2010/06/19 06:00
MHDA- 2010/10/13 06:00
CRDT- 2010/06/19 06:00
PHST- 2010/06/19 06:00 [entrez]
PHST- 2010/06/19 06:00 [pubmed]
PHST- 2010/10/13 06:00 [medline]
AID - 10.1055/s-0029-1245475 [doi]
PST - ppublish
SO  - Klin Monbl Augenheilkd. 2010 Jun;227(6):460-6. doi: 10.1055/s-0029-1245475. Epub 
      2010 Jun 17.