PMID- 20560888
OWN - NLM
STAT- MEDLINE
DCOM- 20110407
LR  - 20110128
IS  - 1755-3768 (Electronic)
IS  - 1755-375X (Linking)
VI  - 89
IP  - 1
DP  - 2011 Feb
TI  - Analysis of spectral domain optical coherence tomography findings in occult 
      macular dystrophy.
PG  - e52-6
LID - 10.1111/j.1755-3768.2010.01958.x [doi]
AB  - PURPOSE: To describe findings of spectral domain optical coherence tomography 
      (SD-OCT) in the diagnosis of occult macular dystrophy (OMD). MATERIALS AND 
      METHODS: Five visually disturbed patients who had shown normal findings in full 
      field electroretinogram (ERG), fundus photography and fluorescein angiography but 
      abnormal findings in multifocal ERG had undergone SD-OCT. The morphologic changes 
      in retina and macular thickness were detected and imaged by SD-OCT. We analysed 
      the results of SD-OCT including macular thickness, inner segment and outer 
      segment (IS/OS) boundary and external limiting membrane (ELM). RESULTS: Mean age 
      was 41.6 (22-63) in three male and two female patients in this study. Mean 
      central foveal thickness was 142.9 (76-161) mum. All patients had shown decreased 
      bowing of IS/OS boundary, and five of nine eyes were noted with disrupted IS/OS 
      boundary of the photoreceptors according to SD-OCT. The interruption of external 
      limiting membrane was noted in three of nine eyes. CONCLUSIONS: Spectral domain 
      optical coherence tomography findings are useful in diagnosing OMD. Morphologic 
      changes of the retina including deformity of the OS/IS boundary of the 
      photoreceptors, disruption of the ELM and decreased foveal thickness may be 
      important characteristics to consider when determining the pathophysiology and 
      diagnosing criteria of OMD.
CI  - (c) 2010 The Authors. Journal compilation (c) 2010 Acta Ophthalmol.
FAU - Kim, Young-Gyun
AU  - Kim YG
AD  - Department of Ophthalmology, Eulji University, Eulji General Hospital, Seoul, 
      Korea.
FAU - Baek, Seung-Hee
AU  - Baek SH
FAU - Moon, Sang Woong
AU  - Moon SW
FAU - Lee, Ho-Kyung
AU  - Lee HK
FAU - Kim, Ungsoo Samuel
AU  - Kim US
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - England
TA  - Acta Ophthalmol
JT  - Acta ophthalmologica
JID - 101468102
SB  - IM
MH  - Adult
MH  - Electroretinography
MH  - Female
MH  - Fluorescein Angiography
MH  - Humans
MH  - Macular Degeneration/*diagnosis
MH  - Male
MH  - Middle Aged
MH  - Retina/pathology
MH  - *Tomography, Optical Coherence
MH  - Young Adult
EDAT- 2010/06/22 06:00
MHDA- 2011/04/08 06:00
CRDT- 2010/06/22 06:00
PHST- 2010/06/22 06:00 [entrez]
PHST- 2010/06/22 06:00 [pubmed]
PHST- 2011/04/08 06:00 [medline]
AID - AOS1958 [pii]
AID - 10.1111/j.1755-3768.2010.01958.x [doi]
PST - ppublish
SO  - Acta Ophthalmol. 2011 Feb;89(1):e52-6. doi: 10.1111/j.1755-3768.2010.01958.x.