PMID- 20563841
OWN - NLM
STAT- MEDLINE
DCOM- 20101228
LR  - 20211020
IS  - 1573-3017 (Electronic)
IS  - 0963-9292 (Linking)
VI  - 19
IP  - 7
DP  - 2010 Oct
TI  - Exposure to persistent organic pollutants (POPs) and DNA damage as an indicator 
      of environmental stress in fish of different feeding habits of Coatzacoalcos, 
      Veracruz, Mexico.
PG  - 1238-48
LID - 10.1007/s10646-010-0508-x [doi]
AB  - The region of Coatzacoalcos, Veracruz hosts one of the largest and most important 
      industrial areas of Mexico and Latin America. Industrial development and rapid 
      population growth, have triggered a severe impact on aquatic ecosystems of the 
      region. The aim of this study was to determine the levels of POPs in sediment and 
      in muscle tissue of five fish species from different trophic levels in downstream 
      residents of the Coatzacoalcos River, and their integration with DNA damage in 
      the fish, evaluated with the comet assay in whole blood as a biological indicator 
      of stress, in order to obtain a baseline of the ecological condition of the 
      region. The compounds detected in sediment and in muscle tissue were 
      hexachlorobenzene (HCB), alpha-, beta-, gamma-hexachlorocyclohexane (HCH), 
      dichlorodiphenyltrichloroethane (DDT), dichlorodiphenyldichloroethylene (DDE), 
      mirex and polychlorinated biphenyls (PCBs). Sediment concentrations of these 
      pollutants (except for mirex) exceeded the values of protection provided by 
      international guidelines, suggesting a potential risk to aquatic life in the 
      region. DNA damage recorded in the fish species is evidence of exposure to a mix 
      of genotoxic pollutants, which combined with exposure to POPs, reflects the 
      degree of environmental stress of aquatic organisms in the region. The results of 
      this study show the importance of determining the presence of contaminants in the 
      environment, the bioaccumulation in tissues and their effects on exposed 
      organisms, providing an integrated approach in assessing the health of aquatic 
      ecosystems.
FAU - Gonzalez-Mille, Donaji J
AU  - Gonzalez-Mille DJ
AD  - Departamento de Toxicologia Ambiental, Facultad de Medicina, Universidad Autonoma 
      de San Luis Potosi, Avenida Venustiano Carranza 2405, Col. Lomas Los Filtros, San 
      Luis Potosi, SLP, CP 78210, Mexico.
FAU - Ilizaliturri-Hernandez, Cesar A
AU  - Ilizaliturri-Hernandez CA
FAU - Espinosa-Reyes, Guillermo
AU  - Espinosa-Reyes G
FAU - Costilla-Salazar, Rogelio
AU  - Costilla-Salazar R
FAU - Diaz-Barriga, Fernando
AU  - Diaz-Barriga F
FAU - Ize-Lema, Irina
AU  - Ize-Lema I
FAU - Mejia-Saavedra, Jesus
AU  - Mejia-Saavedra J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100620
PL  - United States
TA  - Ecotoxicology
JT  - Ecotoxicology (London, England)
JID - 9885956
RN  - 0 (Industrial Waste)
RN  - 0 (Water Pollutants, Chemical)
RN  - 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene)
RN  - 4Z87H0LKUY (Hexachlorobenzene)
RN  - 59NEE7PCAB (Hexachlorocyclohexane)
RN  - CIW5S16655 (DDT)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
RN  - Z917AN264P (Mirex)
SB  - IM
MH  - Animals
MH  - Comet Assay
MH  - DDT/blood/toxicity
MH  - *DNA Damage
MH  - Dichlorodiphenyl Dichloroethylene/blood/toxicity
MH  - Environmental Monitoring/*methods
MH  - Fishes/blood/*physiology
MH  - Geologic Sediments/chemistry
MH  - Hexachlorobenzene/blood/toxicity
MH  - Hexachlorocyclohexane/blood/toxicity
MH  - Industrial Waste/adverse effects
MH  - Latin America
MH  - Mexico
MH  - Mirex/toxicity
MH  - Muscles/chemistry
MH  - Polychlorinated Biphenyls/blood/toxicity
MH  - Rivers
MH  - Water Pollutants, Chemical/analysis/*blood
EDAT- 2010/06/22 06:00
MHDA- 2010/12/29 06:00
CRDT- 2010/06/22 06:00
PHST- 2010/06/02 00:00 [accepted]
PHST- 2010/06/22 06:00 [entrez]
PHST- 2010/06/22 06:00 [pubmed]
PHST- 2010/12/29 06:00 [medline]
AID - 10.1007/s10646-010-0508-x [doi]
PST - ppublish
SO  - Ecotoxicology. 2010 Oct;19(7):1238-48. doi: 10.1007/s10646-010-0508-x. Epub 2010 
      Jun 20.