PMID- 20565080
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20101104
LR  - 20100729
IS  - 1520-6882 (Electronic)
IS  - 0003-2700 (Linking)
VI  - 82
IP  - 14
DP  - 2010 Jul 15
TI  - Convenient method for modifying poly(dimethylsiloxane) to be airtight and 
      resistive against absorption of small molecules.
PG  - 5965-71
LID - 10.1021/ac100830t [doi]
AB  - In this paper we present a simple and rapid method of modifying 
      poly(dimethylsiloxane) (PDMS) surfaces with paraffin wax. PDMS that contains a 
      layer of paraffin wax at its surface resists the absorption of hydrophobic 
      molecules; we used fluorescence microscopy to confirm that paraffin-modified PDMS 
      resists the absorption of rhodamine B. Furthermore, we demonstrated that 
      microfluidic devices made from PDMS that contains a surface layer of paraffin wax 
      prevent efficiently the transport of gas molecules through the bulk and into 
      microchannels. We characterized the surface of PDMS that contains paraffin wax 
      using the water contact angle, optical transmission, and X-ray photoelectron 
      spectroscopy. We show that PDMS that contains paraffin wax can be substituted for 
      native PDMS; specifically, we fabricated peristaltic valves in PDMS that contains 
      paraffin wax, and the valves showed no degradation in performance after multiple 
      open/close cycles. Finally, we show how to use PDMS that has been treated with 
      paraffin wax as a mold for the fabrication of PDMS replicas; this approach avoids 
      silanization of PDMS, which is a time-consuming step in soft lithography. The 
      wax-modified PDMS channels also show performance superiro to that of bare PDMS in 
      micellar electrokinetic chromatography for quantitative analysis.
FAU - Ren, Kangning
AU  - Ren K
AD  - Department of Chemistry, The Hong Kong University of Science and Technology, 
      Clear Water Bay, Kowloon, Hong Kong, China.
FAU - Zhao, Yihua
AU  - Zhao Y
FAU - Su, Jing
AU  - Su J
FAU - Ryan, Declan
AU  - Ryan D
FAU - Wu, Hongkai
AU  - Wu H
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Anal Chem
JT  - Analytical chemistry
JID - 0370536
EDAT- 2010/06/23 06:00
MHDA- 2010/06/23 06:01
CRDT- 2010/06/23 06:00
PHST- 2010/06/23 06:00 [entrez]
PHST- 2010/06/23 06:00 [pubmed]
PHST- 2010/06/23 06:01 [medline]
AID - 10.1021/ac100830t [doi]
PST - ppublish
SO  - Anal Chem. 2010 Jul 15;82(14):5965-71. doi: 10.1021/ac100830t.