PMID- 20570362
OWN - NLM
STAT- MEDLINE
DCOM- 20101020
LR  - 20101004
IS  - 1549-4713 (Electronic)
IS  - 0161-6420 (Linking)
VI  - 117
IP  - 10
DP  - 2010 Oct
TI  - High-resolution optical coherence tomography after surgery for vitreomacular 
      traction: a 2-year follow-up.
PG  - 2010-7, 2017.e1-2
LID - 10.1016/j.ophtha.2010.01.041 [doi]
AB  - PURPOSE: To characterize the morphologic changes in vitreomacular traction (VMT) 
      before and after surgery using spectral-domain optical coherence tomography (SD 
      OCT) and to identify patterns relevant to visual function. DESIGN: Prospective, 
      interventional case series. PARTICIPANTS: Thirty eyes of 30 consecutive patients 
      with visual acuity of less than 20/32 resulting from idiopathic VMT. METHODS: A 
      conventional 20-gauge 3-port vitrectomy was performed, including removal of the 
      epiretinal membrane (ERM) and internal limiting membrane. Examinations were 
      performed 1 day before surgery and 1 and 3 days as well as 1, 3, 6, 12, and 24 
      months after surgery. The SD OCT scan sets were analyzed with regard to central 
      retinal thickness (CRT), retinal volume (RV), graded parameters of inner/outer 
      retinal layer integrity (ILI/OLI), presence of retinal surface folds (RSF), and 
      foveal contour. MAIN OUTCOME MEASURES: Visual acuity and morphologic 
      characteristics of the inner and outer retinal layers revealed by SD OCT. 
      RESULTS: Spectral-domain OCT revealed a complete absence of the ERM and early 
      release of traction forces in each eye. Best-corrected visual acuity increased 
      progressively over 24 months. Morphologically, RSF resolved within 1 month after 
      surgery, followed by a marked decrease in CRT and RV over the next 3 months. 
      There was no significantly correlation between RSF, CRT, or RV with functional 
      improvement, and CRT and RV did not return to physiologic values. Recovery of ILI 
      and OLI proceeded slowly, reaching significance at 12 months, and correlated 
      strongly with visual function. CONCLUSIONS: Spectral-domain OCT seems to be a 
      valuable method for evaluating retinal changes after surgery for VMT. 
      Reconstitution of neurosensory layers was identified as the most relevant 
      parameter for visual improvement.
CI  - Copyright (c) 2010 American Academy of Ophthalmology. Published by Elsevier Inc. 
      All rights reserved.
FAU - Sayegh, Ramzi G
AU  - Sayegh RG
AD  - Department of Ophthalmology, Medical University of Vienna, Vienna, Austria.
FAU - Georgopoulos, Michael
AU  - Georgopoulos M
FAU - Geitzenauer, Wolfgang
AU  - Geitzenauer W
FAU - Simader, Christian
AU  - Simader C
FAU - Kiss, Christopher
AU  - Kiss C
FAU - Schmidt-Erfurth, Ursula
AU  - Schmidt-Erfurth U
LA  - eng
PT  - Journal Article
DEP - 20100608
PL  - United States
TA  - Ophthalmology
JT  - Ophthalmology
JID - 7802443
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Basement Membrane/pathology/surgery
MH  - Epiretinal Membrane/*diagnosis/surgery
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Macula Lutea/*pathology
MH  - Male
MH  - Middle Aged
MH  - Postoperative Period
MH  - Prospective Studies
MH  - Tissue Adhesions
MH  - *Tomography, Optical Coherence
MH  - Traction
MH  - Visual Acuity/physiology
MH  - Vitrectomy
MH  - Vitreous Body/*pathology
EDAT- 2010/06/24 06:00
MHDA- 2010/10/21 06:00
CRDT- 2010/06/24 06:00
PHST- 2009/06/18 00:00 [received]
PHST- 2010/01/14 00:00 [revised]
PHST- 2010/01/25 00:00 [accepted]
PHST- 2010/06/24 06:00 [entrez]
PHST- 2010/06/24 06:00 [pubmed]
PHST- 2010/10/21 06:00 [medline]
AID - S0161-6420(10)00114-4 [pii]
AID - 10.1016/j.ophtha.2010.01.041 [doi]
PST - ppublish
SO  - Ophthalmology. 2010 Oct;117(10):2010-7, 2017.e1-2. doi: 
      10.1016/j.ophtha.2010.01.041. Epub 2010 Jun 8.