PMID- 20580906
OWN - NLM
STAT- MEDLINE
DCOM- 20101004
LR  - 20191210
IS  - 1876-861X (Electronic)
IS  - 1876-861X (Linking)
VI  - 4
IP  - 4
DP  - 2010 Jul-Aug
TI  - Cardiac computed tomography for prediction of myocardial viability after 
      reperfused acute myocardial infarction.
PG  - 267-73
LID - 10.1016/j.jcct.2010.04.004 [doi]
AB  - BACKGROUND: Perfusion defects (PDs) detected with cardiac magnetic resonance 
      (CMR) imaging predict the functional recovery of myocardial function after acute 
      myocardial infarction. OBJECTIVE: We evaluated the ability of cardiac computed 
      tomography (CCT) to predict the recovery of regional left ventricular (LV) 
      systolic function after ST elevation myocardial infarction (STEMI). METHODS: 
      Seventeen patients (mean age, 60610 years) presenting with STEMI were 
      prospectively studied. Each patient underwent CCT and CMR at baseline and after 
      an average of 6 months. Areas of PD were quantified. Segmental LV systolic 
      function was semiquantitatively assessed by CMR. An improvement at 6 months by R1 
      category in the regional wall motion score was considered LV recovery. RESULTS: 
      Coronary artery revascularization was successfully performed with post procedural 
      TIMI 3 flow in 16 cases. On CCT assessment, 107 of 289 segments (37%) had some 
      degree of PD. On follow-up, segments with,25%PD at baseline had no worsening of 
      wall motion. In segments with.75%PD, 89% (9 of 11) showed akinesis or worsening 
      of wall motion. The odds ratio for improvement in segmental wall motion with 
      increasing PD category was 0.63 (95% CI, 0.42-0.97; P 5 0.035). The degree of PD 
      on CT predicted LV recovery at follow-up (P , 0.0001). CONCLUSIONS: The 
      transmural extent of myocardial infarction as detected and quantified with CCT 
      predicts the recovery of regional systolic LV function after revascularization 
      for acute STEMI.
CI  - Copyright 2010 Society of Cardiovascular Computed Tomography.
FAU - Shapiro, Michael D
AU  - Shapiro MD
AD  - Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical 
      School, Boston, MA, USA.
FAU - Sarwar, Ammar
AU  - Sarwar A
FAU - Nieman, Koen
AU  - Nieman K
FAU - Nasir, Khurram
AU  - Nasir K
FAU - Brady, Thomas J
AU  - Brady TJ
FAU - Cury, Ricardo C
AU  - Cury RC
LA  - eng
GR  - 1T32 HL076136-02/HL/NHLBI NIH HHS/United States
PT  - Comment
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - J Cardiovasc Comput Tomogr
JT  - Journal of cardiovascular computed tomography
JID - 101308347
RN  - 0 (Contrast Media)
RN  - 0 (Triiodobenzoic Acids)
RN  - HW8W27HTXX (iodixanol)
SB  - IM
CON - J Cardiovasc Comput Tomogr. 2010 Jul-Aug;4(4):274-5. PMID: 20579618
MH  - Aged
MH  - Chi-Square Distribution
MH  - Contrast Media
MH  - Coronary Circulation
MH  - Female
MH  - Humans
MH  - Logistic Models
MH  - Magnetic Resonance Imaging, Cine
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/*diagnostic imaging/physiopathology/therapy
MH  - Myocardial Perfusion Imaging/*methods
MH  - Myocardial Revascularization
MH  - Myocardium/*pathology
MH  - Predictive Value of Tests
MH  - Prospective Studies
MH  - Radiographic Image Interpretation, Computer-Assisted
MH  - Recovery of Function
MH  - Time Factors
MH  - Tissue Survival
MH  - *Tomography, X-Ray Computed
MH  - Treatment Outcome
MH  - Triiodobenzoic Acids
MH  - Ventricular Function, Left
EDAT- 2010/06/29 06:00
MHDA- 2010/10/05 06:00
CRDT- 2010/06/29 06:00
PHST- 2009/12/06 00:00 [received]
PHST- 2010/04/03 00:00 [revised]
PHST- 2010/04/06 00:00 [accepted]
PHST- 2010/06/29 06:00 [entrez]
PHST- 2010/06/29 06:00 [pubmed]
PHST- 2010/10/05 06:00 [medline]
AID - S1934-5925(10)00256-X [pii]
AID - 10.1016/j.jcct.2010.04.004 [doi]
PST - ppublish
SO  - J Cardiovasc Comput Tomogr. 2010 Jul-Aug;4(4):267-73. doi: 
      10.1016/j.jcct.2010.04.004.