PMID- 20583986
OWN - NLM
STAT- MEDLINE
DCOM- 20110316
LR  - 20190907
IS  - 1873-4294 (Electronic)
IS  - 1568-0266 (Linking)
VI  - 10
IP  - 16
DP  - 2010
TI  - Radioligands for the angiotensin II subtype 1 (AT1) receptor.
PG  - 1585-99
AB  - Over the last years, ligands for angiotensin II subtype 1 receptor (AT1R) have 
      been developed as an alternative to the use of angiotensin-converting enzyme 
      (ACE) inhibitors for controlling high blood pressure. Radiolabeled versions of 
      these ligands have proven vital to the development of more potent and specific 
      drugs for the treatment of hypertension. Imaging studies using radiolabeled AT1R 
      ligands have also elucidated the role these receptors play in angiogenesis as 
      well as in various disease states beyond hypertension.
FAU - Mathews, William B
AU  - Mathews WB
AD  - Johns Hopkins University School of Medicine, USA. bmathews@jhu.edu
FAU - Szabo, Zsolt
AU  - Szabo Z
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United Arab Emirates
TA  - Curr Top Med Chem
JT  - Current topics in medicinal chemistry
JID - 101119673
RN  - 0 (Ligands)
RN  - 0 (Radioisotopes)
RN  - 0 (Receptor, Angiotensin, Type 1)
SB  - IM
MH  - Animals
MH  - Humans
MH  - Ligands
MH  - Molecular Structure
MH  - Radioisotopes
MH  - *Radioligand Assay
MH  - Receptor, Angiotensin, Type 1/*metabolism
MH  - Stereoisomerism
EDAT- 2010/06/30 06:00
MHDA- 2011/03/17 06:00
CRDT- 2010/06/30 06:00
PHST- 2009/11/13 00:00 [received]
PHST- 2010/01/18 00:00 [accepted]
PHST- 2010/06/30 06:00 [entrez]
PHST- 2010/06/30 06:00 [pubmed]
PHST- 2011/03/17 06:00 [medline]
AID - BSP/ CTMC /E-Pub/-0104-10-16 [pii]
AID - 10.2174/156802610793176729 [doi]
PST - ppublish
SO  - Curr Top Med Chem. 2010;10(16):1585-99. doi: 10.2174/156802610793176729.