PMID- 20595470
OWN - NLM
STAT- MEDLINE
DCOM- 20100810
LR  - 20211020
IS  - 1476-1645 (Electronic)
IS  - 0002-9637 (Print)
IS  - 0002-9637 (Linking)
VI  - 83
IP  - 1
DP  - 2010 Jul
TI  - Unmasking leprosy: an unusual immune reconstitution inflammatory syndrome in a 
      patient infected with human immunodeficiency virus.
PG  - 13-4
LID - 10.4269/ajtmh.2010.10-0071 [doi]
AB  - Immune reconstitution inflammatory syndrome (IRIS) has become a frequent and 
      potentially severe complication after initiation of following antiretroviral 
      therapy (ART) in patients infected with human immunodeficiency virus (HIV). IRIS 
      can unmask a previously clinically silent infection, such as tuberculosis, as 
      recently described for Mycobacterium infections. We describe a case in a patient 
      from Cote d'Ivoire living in France in whom skin papular lesions developed after 
      initiation of ART. These lesions were associated with microbiologically proven 
      leprosy. Thus, latent leprosy can appear as IRIS, and leprosy-associated IRIS 
      should be considered in HIV-infected patients from areas endemic for leprosy.
FAU - Bussone, Guillaume
AU  - Bussone G
AD  - Service de Maladies Infectieuses et Tropicales, et Service de Microbiologie, 
      Centre d'Infectiologie Necker-Pasteur, Universite Paris Descartes, Hopital 
      Necker-Enfants Malades, Assistance Publique-Hopitaux de Paris, Paris, France.
FAU - Charlier, Caroline
AU  - Charlier C
FAU - Bille, Emmanuelle
AU  - Bille E
FAU - Caux, Frederic
AU  - Caux F
FAU - Levy, Annie
AU  - Levy A
FAU - Viard, Jean-Paul
AU  - Viard JP
FAU - Lecuit, Marc
AU  - Lecuit M
FAU - Lortholary, Olivier
AU  - Lortholary O
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Am J Trop Med Hyg
JT  - The American journal of tropical medicine and hygiene
JID - 0370507
SB  - IM
MH  - HIV Infections/*complications/drug therapy
MH  - Humans
MH  - Immune Reconstitution Inflammatory Syndrome/complications/*etiology
MH  - Leprosy/epidemiology/*etiology
PMC - PMC2912568
EDAT- 2010/07/03 06:00
MHDA- 2010/08/11 06:00
PMCR- 2011/07/01
CRDT- 2010/07/03 06:00
PHST- 2010/07/03 06:00 [entrez]
PHST- 2010/07/03 06:00 [pubmed]
PHST- 2010/08/11 06:00 [medline]
PHST- 2011/07/01 00:00 [pmc-release]
AID - 83/1/13 [pii]
AID - 10.4269/ajtmh.2010.10-0071 [doi]
PST - ppublish
SO  - Am J Trop Med Hyg. 2010 Jul;83(1):13-4. doi: 10.4269/ajtmh.2010.10-0071.