PMID- 20603578 OWN - NLM STAT- MEDLINE DCOM- 20100812 LR - 20221207 IS - 1598-6535 (Print) IS - 1598-6535 (Linking) VI - 30 IP - 3 DP - 2010 Jun TI - [New HLA nomenclature (2010) and its clinical application in Koreans]. PG - 203-17 LID - 10.3343/kjlm.2010.30.3.203 [doi] AB - Human leukocyte antigen (HLA) gene region encodes a set of HLA molecules functioning critical roles in immune response. Each HLA gene locus shows extensive polymorphism with ever-increasing number of alleles. The HLA nomenclature system for alleles defined by DNA typing was first established in 1987 and has been revised several times. Recently, it has been revised again with a new frame that can accommodate ever-increasing number of new alleles. The new system has also introduced the novel suffixes, P and G, to simplify reporting of ambiguous strings of alleles in typing reports. This review introduces the HLA nomenclature system-2010 in conjunction with its clinical application in Koreans. FAU - Lee, Kyung Wha AU - Lee KW AD - Hallym Institution for Genome Application, Hallym University College of Medicine, Anyang, Korea. leekw@hallym.or.kr FAU - Park, Myoung Hee AU - Park MH LA - kor PT - Journal Article PT - Review PL - Korea (South) TA - Korean J Lab Med JT - The Korean journal of laboratory medicine JID - 101322822 RN - 0 (HLA Antigens) SB - IM MH - Alleles MH - Asian People/*genetics MH - HLA Antigens/classification/*genetics MH - Humans MH - Republic of Korea MH - *Terminology as Topic RF - 17 EDAT- 2010/07/07 06:00 MHDA- 2010/08/13 06:00 CRDT- 2010/07/07 06:00 PHST- 2010/07/07 06:00 [entrez] PHST- 2010/07/07 06:00 [pubmed] PHST- 2010/08/13 06:00 [medline] AID - 201006203 [pii] AID - 10.3343/kjlm.2010.30.3.203 [doi] PST - ppublish SO - Korean J Lab Med. 2010 Jun;30(3):203-17. doi: 10.3343/kjlm.2010.30.3.203.