PMID- 20604891
OWN - NLM
STAT- MEDLINE
DCOM- 20110406
LR  - 20111117
IS  - 1399-0039 (Electronic)
IS  - 0001-2815 (Linking)
VI  - 76
IP  - 4
DP  - 2010 Oct
TI  - Sixty-five novel alleles at the HLA-A, -B, and -DRB1 loci identified from 
      National Marrow Donor Program volunteer donors.
PG  - 319-24
LID - 10.1111/j.1399-0039.2010.01524.x [doi]
AB  - Sixty-five novel human leukocyte antigen (HLA) alleles are described from 
      volunteer donors of the 'Be The Match Registry': 29 HLA-A alleles, 24 HLA-B 
      alleles, and 12 HLA-DRB1 alleles. Eight ( approximately 12%) of the novel alleles were found in 
      more than one individual and may be more common in the population. Forty ( approximately 62%) 
      of the 65 novel alleles are single nucleotide substitution variants when compared 
      with their most homologous allele. Two of these single nucleotide variants are 
      silent substitutions and one creates a null allele. The remaining novel alleles 
      differ from their most similar allele by 2-10 nucleotide substitutions. Some of 
      the novel alleles encode amino acid changes at codons not previously reported to 
      be polymorphic, such as codons 23, 93, 129, and 155 in HLA-A alleles and codon 3 
      in HLA-B alleles.
CI  - (c) 2010 John Wiley & Sons A/S.
FAU - Lazaro, A M
AU  - Lazaro AM
AD  - Department of Oncology and C. W. Bill Young Marrow Donor Research and Recruitment 
      Program, Georgetown University Medical Center, Washington, DC 20057, USA.
FAU - Xiao, Y
AU  - Xiao Y
FAU - Regenscheid, A
AU  - Regenscheid A
FAU - Ng, J
AU  - Ng J
FAU - Hurley, C K
AU  - Hurley CK
FAU - Posch, P E
AU  - Posch PE
LA  - eng
SI  - GENBANK/EU682448
SI  - GENBANK/EU682449
SI  - GENBANK/EU682450
SI  - GENBANK/EU716062
SI  - GENBANK/EU716063
SI  - GENBANK/EU716064
SI  - GENBANK/EU716065
SI  - GENBANK/EU716068
SI  - GENBANK/EU812536
SI  - GENBANK/EU812537
SI  - GENBANK/EU812540
SI  - GENBANK/EU812541
SI  - GENBANK/EU826129
SI  - GENBANK/EU826130
SI  - GENBANK/EU924807
SI  - GENBANK/EU924810
SI  - GENBANK/FJ174579
SI  - GENBANK/FJ174580
SI  - GENBANK/FJ187800
SI  - GENBANK/FJ187801
SI  - GENBANK/FJ196569
SI  - GENBANK/FJ358708
SI  - GENBANK/FJ358709
SI  - GENBANK/FJ358710
SI  - GENBANK/FJ358711
SI  - GENBANK/FJ358712
SI  - GENBANK/FJ464344
SI  - GENBANK/FJ464345
SI  - GENBANK/FJ464347
SI  - GENBANK/FJ464348
SI  - GENBANK/FJ464349
SI  - GENBANK/FJ464350
SI  - GENBANK/FJ464351
SI  - GENBANK/FJ464354
SI  - GENBANK/FJ517141
SI  - GENBANK/FJ517142
SI  - GENBANK/FJ517143
SI  - GENBANK/FJ517144
SI  - GENBANK/FJ517145
SI  - GENBANK/FJ517146
SI  - GENBANK/FJ517147
SI  - GENBANK/FJ619477
SI  - GENBANK/FJ619478
SI  - GENBANK/FJ619479
SI  - GENBANK/FJ619481
SI  - GENBANK/FJ619493
SI  - GENBANK/FJ619494
SI  - GENBANK/FJ619495
SI  - GENBANK/FJ619496
SI  - GENBANK/FJ619497
SI  - GENBANK/FJ619498
SI  - GENBANK/FJ619499
SI  - GENBANK/FJ619500
SI  - GENBANK/FJ619501
SI  - GENBANK/FJ619502
SI  - GENBANK/FJ649610
SI  - GENBANK/FJ649611
SI  - GENBANK/FJ649612
SI  - GENBANK/FJ688158
SI  - GENBANK/FJ688159
SI  - GENBANK/FJ688160
SI  - GENBANK/FJ688161
SI  - GENBANK/FJ688162
SI  - GENBANK/FJ688163
SI  - GENBANK/FJ688164
SI  - GENBANK/FJ688166
SI  - GENBANK/FJ688167
SI  - GENBANK/FJ842971
SI  - GENBANK/GO410122
SI  - GENBANK/GO410123
SI  - GENBANK/GO867219
SI  - GENBANK/GU066739
SI  - GENBANK/GU066742
SI  - GENBANK/GU066761
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-DR Antigens)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - *Alleles
MH  - Bone Marrow
MH  - HLA-A Antigens/*genetics
MH  - HLA-B Antigens/*genetics
MH  - HLA-DR Antigens/*genetics
MH  - HLA-DRB1 Chains
MH  - Humans
MH  - Molecular Sequence Data
MH  - *Registries
MH  - *Tissue Donors
EDAT- 2010/07/08 06:00
MHDA- 2011/04/07 06:00
CRDT- 2010/07/08 06:00
PHST- 2010/07/08 06:00 [entrez]
PHST- 2010/07/08 06:00 [pubmed]
PHST- 2011/04/07 06:00 [medline]
AID - TAN1524 [pii]
AID - 10.1111/j.1399-0039.2010.01524.x [doi]
PST - ppublish
SO  - Tissue Antigens. 2010 Oct;76(4):319-24. doi: 10.1111/j.1399-0039.2010.01524.x.