PMID- 20608361 OWN - NLM STAT- MEDLINE DCOM- 20101007 LR - 20100708 IS - 1009-3591 (Print) IS - 1009-3591 (Linking) VI - 16 IP - 6 DP - 2010 Jun TI - [Male factors in repeated spontaneous abortion]. PG - 542-6 AB - Repeated spontaneous abortion (RSA), with very complicated pathogenesis, has an incidence of about 0.5% 2.0%. As for the paternal part which provides half of the genes for the embryo, current studies mainly focus on the genes of somatic cells or germ cells. Chromosome abnormality of somatic cells, chromosome disorder of sperm, defects in sperm quality, genetic mutation, senility, infection and any other paternal gene abnormalities that affect the embryo would induce RSA. This paper presents an update on the above mentioned paternal factors which might result in RSA. FAU - Pan, Feng AU - Pan F AD - Department of Andrology and Urology, Nanjing Maternity and Child Healthcare Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu 210004, China. panfeng27@yahoo.com.cn FAU - Zhang, Ai-Xia AU - Zhang AX FAU - Pan, Lian-Jun AU - Pan LJ LA - chi PT - English Abstract PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - China TA - Zhonghua Nan Ke Xue JT - Zhonghua nan ke xue = National journal of andrology JID - 101093592 SB - IM MH - Abortion, Spontaneous/*etiology MH - Chromosomes, Human, Y MH - DNA Damage MH - Female MH - Humans MH - Male MH - Pregnancy MH - *Spermatozoa RF - 32 EDAT- 2010/07/09 06:00 MHDA- 2010/10/12 06:00 CRDT- 2010/07/09 06:00 PHST- 2010/07/09 06:00 [entrez] PHST- 2010/07/09 06:00 [pubmed] PHST- 2010/10/12 06:00 [medline] PST - ppublish SO - Zhonghua Nan Ke Xue. 2010 Jun;16(6):542-6.