PMID- 20621291 OWN - NLM STAT- MEDLINE DCOM- 20101129 LR - 20100816 IS - 1879-0534 (Electronic) IS - 0010-4825 (Linking) VI - 40 IP - 8 DP - 2010 Aug TI - Tackling EEG signal classification with least squares support vector machines: a sensitivity analysis study. PG - 705-14 LID - 10.1016/j.compbiomed.2010.06.005 [doi] AB - The electroencephalogram (EEG) signal captures the electrical activity of the brain and is an important source of information for studying neurological disorders. The proper analysis of this biological signal plays an important role in the domain of brain-computer interface, which aims at the construction of communication channels between human brain and computers. In this paper, we investigate the application of least squares support vector machines (LS-SVM) to the task of epilepsy diagnosis through automatic EEG signal classification. More specifically, we present a sensitivity analysis study by means of which the performance levels exhibited by standard and least squares SVM classifiers are contrasted, taking into account the setting of the kernel function and of its parameter value. Results of experiments conducted over different types of features extracted from a benchmark EEG signal dataset evidence that the sensitivity profiles of the kernel machines are qualitatively similar, both showing notable performance in terms of accuracy and generalization. In addition, the performance accomplished by optimally configured LS-SVM models is also quantitatively contrasted with that obtained by related approaches for the same dataset. CI - Copyright 2010 Elsevier Ltd. All rights reserved. FAU - Lima, Clodoaldo A M AU - Lima CA AD - Graduate Program in Electrical Engineering, School of Engineering, Mackenzie Presbyterian University, Rua da Consolacao, 896, 01302-907 Sao Paulo, SP, Brazil. moraes@mackenzie.br FAU - Coelho, Andre L V AU - Coelho AL FAU - Eisencraft, Marcio AU - Eisencraft M LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Comput Biol Med JT - Computers in biology and medicine JID - 1250250 SB - IM MH - *Algorithms MH - *Artificial Intelligence MH - Brain/physiology/physiopathology MH - Electroencephalography/*methods MH - Epilepsy/physiopathology MH - Humans MH - Least-Squares Analysis MH - *Signal Processing, Computer-Assisted EDAT- 2010/07/14 06:00 MHDA- 2010/12/14 06:00 CRDT- 2010/07/13 06:00 PHST- 2009/09/01 00:00 [received] PHST- 2010/04/19 00:00 [revised] PHST- 2010/06/11 00:00 [accepted] PHST- 2010/07/13 06:00 [entrez] PHST- 2010/07/14 06:00 [pubmed] PHST- 2010/12/14 06:00 [medline] AID - S0010-4825(10)00087-9 [pii] AID - 10.1016/j.compbiomed.2010.06.005 [doi] PST - ppublish SO - Comput Biol Med. 2010 Aug;40(8):705-14. doi: 10.1016/j.compbiomed.2010.06.005.