PMID- 20635285 OWN - NLM STAT- MEDLINE DCOM- 20101102 LR - 20211020 IS - 1545-0848 (Electronic) IS - 1055-0887 (Print) IS - 1055-0887 (Linking) VI - 29 IP - 3 DP - 2010 Jul TI - Hepatitis C treatment eligibility and comorbid medical illness in methadone maintenance (MMT) and non-MMT patients: a case-control study. PG - 359-69 LID - 10.1080/10550887.2010.489449 [doi] AB - Comorbid medical illness is common in patients with chronic hepatitis C (HCV) infection and in methadone treatment (MMT) patients, yet little is known about the impact of medical illness on HCV treatment eligibility. Medical illness and HCV treatment eligibility were compared in a case-control study of 80 MMT patients entering an HCV treatment trial and 80 matched non-MMT patients entering HCV treatment in a gastroenterology clinic. 91% of MMT and 85% of non-MMT patients had chronic medical conditions. Despite similar medical severity ratings, a significantly higher proportion (77%) of non-MMT patients were eligible for HCV treatment than were MMT patients (56%) (p<.01). Specific comorbid medical and psychiatric illness led to ineligibility in only 18% of MMT and 16% of non-MMT patients. However, failure to complete the medical evaluation process was significantly (p<.001) more likely to cause ineligibility among MMT patients (19%) than non-MMT patients (0%). FAU - Batki, Steven L AU - Batki SL AD - San Francisco VA Medical Center, University of California, San Francisco, CA 94121, USA. steven.batki@ucsf.edu FAU - Canfield, Kelly M AU - Canfield KM FAU - Smyth, Emily AU - Smyth E FAU - Ploutz-Snyder, Robert AU - Ploutz-Snyder R FAU - Levine, Robert A AU - Levine RA LA - eng GR - R01 DA016764/DA/NIDA NIH HHS/United States GR - R01 DA016764-06/DA/NIDA NIH HHS/United States GR - R01 DA 016764/DA/NIDA NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PL - England TA - J Addict Dis JT - Journal of addictive diseases JID - 9107051 RN - 0 (Narcotics) RN - UC6VBE7V1Z (Methadone) SB - IM MH - Adult MH - Case-Control Studies MH - Comorbidity MH - Cross-Sectional Studies MH - Eligibility Determination MH - Female MH - Health Services Accessibility/statistics & numerical data MH - *Health Status Indicators MH - Hepatitis C, Chronic/*epidemiology/*rehabilitation MH - Humans MH - Male MH - Mental Disorders/epidemiology/rehabilitation MH - Methadone/*therapeutic use MH - Middle Aged MH - Narcotics/*therapeutic use MH - Opioid-Related Disorders/*epidemiology/*rehabilitation MH - *Patient Selection MH - Substance Abuse, Intravenous/*epidemiology/*rehabilitation PMC - PMC4651622 MID - NIHMS205315 COIS- Disclosure Statement: The authors have no financial or personal conflicts of interest in relation to this publication. EDAT- 2010/07/17 06:00 MHDA- 2010/11/03 06:00 PMCR- 2015/11/18 CRDT- 2010/07/17 06:00 PHST- 2010/07/17 06:00 [entrez] PHST- 2010/07/17 06:00 [pubmed] PHST- 2010/11/03 06:00 [medline] PHST- 2015/11/18 00:00 [pmc-release] AID - 924377213 [pii] AID - 10.1080/10550887.2010.489449 [doi] PST - ppublish SO - J Addict Dis. 2010 Jul;29(3):359-69. doi: 10.1080/10550887.2010.489449.