PMID- 20637768
OWN - NLM
STAT- MEDLINE
DCOM- 20101110
LR  - 20100813
IS  - 1873-2518 (Electronic)
IS  - 0264-410X (Linking)
VI  - 28
IP  - 37
DP  - 2010 Aug 23
TI  - Comparison of commercial and experimental porcine circovirus type 2 (PCV2) 
      vaccines using a triple challenge with PCV2, porcine reproductive and respiratory 
      syndrome virus (PRRSV), and porcine parvovirus (PPV).
PG  - 5960-6
LID - 10.1016/j.vaccine.2010.07.002 [doi]
AB  - The efficacies of commercial porcine circovirus type 2 (PCV2) vaccines and a live 
      PCV1-2a chimeric vaccine were compared in conventional, PCV2-positive piglets 
      using a PCV2-porcine reproductive and respiratory syndrome virus (PRRSV)-porcine 
      parvovirus (PPV) coinfection challenge model. Seventy-three, 2-week-old pigs were 
      randomized into seven groups including five vaccinated and two control groups. 
      Pigs in the vaccinated groups were vaccinated at 3 weeks (one dose) or at 3 and 6 
      weeks (two dose) of age. All vaccine regimens tested were effective in reducing 
      naturally occurring PCV2 viremia at 16 weeks of age and after PCV2 challenge, 
      demonstrating the capability of the products to induce a lasting protective 
      immunity despite the presence of PCV2 viremia at the time of vaccination.
CI  - Copyright 2010 Elsevier Ltd. All rights reserved.
FAU - Shen, H G
AU  - Shen HG
AD  - Department of Veterinary Diagnostic and Production Animal Medicine, College of 
      Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.
FAU - Beach, N M
AU  - Beach NM
FAU - Huang, Y W
AU  - Huang YW
FAU - Halbur, P G
AU  - Halbur PG
FAU - Meng, X J
AU  - Meng XJ
FAU - Opriessnig, T
AU  - Opriessnig T
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100715
PL  - Netherlands
TA  - Vaccine
JT  - Vaccine
JID - 8406899
RN  - 0 (Antibodies, Viral)
RN  - 0 (DNA, Viral)
RN  - 0 (RNA, Viral)
RN  - 0 (Viral Vaccines)
SB  - IM
MH  - Animals
MH  - Antibodies, Viral/blood
MH  - Circoviridae Infections/immunology/prevention & control/*veterinary
MH  - DNA, Viral/blood
MH  - Parvoviridae Infections/immunology/prevention & control/*veterinary
MH  - Parvovirus, Porcine/immunology
MH  - Porcine Reproductive and Respiratory Syndrome/immunology/*prevention & control
MH  - Porcine respiratory and reproductive syndrome virus/immunology
MH  - RNA, Viral/blood
MH  - Swine
MH  - Viral Vaccines/*immunology
EDAT- 2010/07/20 06:00
MHDA- 2010/11/11 06:00
CRDT- 2010/07/20 06:00
PHST- 2010/06/08 00:00 [received]
PHST- 2010/06/28 00:00 [revised]
PHST- 2010/07/01 00:00 [accepted]
PHST- 2010/07/20 06:00 [entrez]
PHST- 2010/07/20 06:00 [pubmed]
PHST- 2010/11/11 06:00 [medline]
AID - S0264-410X(10)00963-1 [pii]
AID - 10.1016/j.vaccine.2010.07.002 [doi]
PST - ppublish
SO  - Vaccine. 2010 Aug 23;28(37):5960-6. doi: 10.1016/j.vaccine.2010.07.002. Epub 2010 
      Jul 15.