PMID- 20638433
OWN - NLM
STAT- MEDLINE
DCOM- 20101214
LR  - 20100906
IS  - 1872-7492 (Electronic)
IS  - 0168-1702 (Linking)
VI  - 153
IP  - 1
DP  - 2010 Oct
TI  - Detection and description of a particular Ostreid herpesvirus 1 genotype 
      associated with massive mortality outbreaks of Pacific oysters, Crassostrea 
      gigas, in France in 2008.
PG  - 92-9
LID - 10.1016/j.virusres.2010.07.011 [doi]
AB  - Ostreid herpesvirus 1 (OsHV-1) infections have been reported around the world and 
      are associated with high mortalities of the Pacific oyster (Crassostrea gigas). 
      In the summer 2008, abnormal mortality rates ranging from 80% to 100% were 
      reported in France and affected only Pacific oysters. Analyses of oyster samples 
      collected during mortality outbreaks demonstrated a significant detection of 
      OsHV-1 (75% of analysed batches), which appeared stronger than previous years. 
      DNA sequencing based on C and IA regions was carried out on 28 batches of OsHV-1 
      infected Pacific oysters collected in 2008. Polymorphisms were described in both 
      the C and IA regions and characterized a genotype of OsHV-1 not already reported 
      and termed OsHV-1 microVar. A microsatellite zone present in the C region showed 
      several deletions. Additionally, 44 isolates collected in France and in the USA, 
      from 1995 to 2007 were sequenced and compared to the 2008 sequences. The analyses 
      of 76 sequences showed OsHV-1 microVar detection only in 2008 isolates. These 
      data suggest that OsHV-1 microVar can be assumed as an emergent genotype.
CI  - (c) 2010 Elsevier B.V. All rights reserved.
FAU - Segarra, Amelie
AU  - Segarra A
AD  - Institut Francais de Recherche pour l'Exploitation de la Mer (IFREMER), 
      Laboratoire de Genetique et Pathologie (LGP), Avenue de Mus de Loup, 17390 La 
      Tremblade, France.
FAU - Pepin, Jean Francois
AU  - Pepin JF
FAU - Arzul, Isabelle
AU  - Arzul I
FAU - Morga, Benjamin
AU  - Morga B
FAU - Faury, Nicole
AU  - Faury N
FAU - Renault, Tristan
AU  - Renault T
LA  - eng
PT  - Journal Article
DEP - 20100716
PL  - Netherlands
TA  - Virus Res
JT  - Virus research
JID - 8410979
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Animals
MH  - Base Sequence
MH  - Crassostrea/*virology
MH  - DNA, Viral/chemistry/*genetics
MH  - France
MH  - Genotype
MH  - Herpesviridae/*classification/genetics/*isolation & purification
MH  - Microsatellite Repeats
MH  - Molecular Sequence Data
MH  - Phylogeny
MH  - *Polymorphism, Genetic
MH  - Sequence Alignment
MH  - Sequence Analysis, DNA
MH  - Sequence Deletion
MH  - Sequence Homology
MH  - United States
EDAT- 2010/07/20 06:00
MHDA- 2010/12/16 06:00
CRDT- 2010/07/20 06:00
PHST- 2010/05/07 00:00 [received]
PHST- 2010/07/08 00:00 [revised]
PHST- 2010/07/08 00:00 [accepted]
PHST- 2010/07/20 06:00 [entrez]
PHST- 2010/07/20 06:00 [pubmed]
PHST- 2010/12/16 06:00 [medline]
AID - S0168-1702(10)00236-4 [pii]
AID - 10.1016/j.virusres.2010.07.011 [doi]
PST - ppublish
SO  - Virus Res. 2010 Oct;153(1):92-9. doi: 10.1016/j.virusres.2010.07.011. Epub 2010 
      Jul 16.