PMID- 20648462 OWN - NLM STAT- MEDLINE DCOM- 20101202 LR - 20100721 IS - 1576-6578 (Electronic) IS - 0210-0010 (Linking) VI - 51 IP - 4 DP - 2010 Aug 16 TI - [Quantitative measurement of axial rigidity, functional status and health-related quality of life in patients with Parkinson's disease]. PG - 193-200 AB - INTRODUCTION: Rigidity is a cardinal symptom of Parkinson's disease (PD). Clinically, rigidity is usually assessed by passively flexing and extending a patient's limb. Few studies have assessed rigidity in trunk muscles in PD patients. AIMS: To develop an objective measurement to quantify trunk rigidity in PD patients, and to examine its relationship with disease severity using the Hoehn and Yahr staging score (HY) and the Unified Parkinson's Disease Rating Scale III (UPDRS-III), disease duration, functional status with the Schwab & England activities of daily living scale and health related quality of life (HRQoL) was assessed with the European Quality of Life-5 Dimensions and Parkinson's Disease Questionnaire-39 items (PDQ-39). PATIENTS AND METHODS: An isokinetic dynamometer Biodex System 3 was employed to assess trunk rigidity in 36 PD patients. Passive trunk flexion and extension at 3 angular velocities, 30 degrees/s, 45 degrees/s and 60 degrees /s were applied and resistive torques were recorded as trunk flexor and extensors rigidity. RESULTS: Significant correlations between trunk flexors-extensors tone and HY staging score, UPDRS-III, disease duration and functional status at 30 degrees/s, 45 degrees/s and 60 degrees/s were obtained. Trunk rigidity was correlated with the HRQoL assessed with the PDQ-39. CONCLUSIONS: Our results suggest that the 30 degrees/s, 45 degrees/s and 60 degrees/s angular velocities of this objective method was valid to assess trunk rigidity and was correlated with disease severity, disease duration, functional status and HRQoL in PD patients. FAU - Cano de la Cuerda, Roberto AU - Cano de la Cuerda R AD - Departamento de Fisioterapia, Terapia Ocupacional, Medicina Fisica y Rehabilitacion, Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos, Alcorcon, Madrid, Espana. roberto.cano@urjc.es FAU - Vela, Lydia AU - Vela L FAU - Miangolarra-Page, Juan Carlos AU - Miangolarra-Page JC FAU - Macias-Macias, Yolanda AU - Macias-Macias Y FAU - Munoz-Hellin, Elena AU - Munoz-Hellin E LA - spa PT - English Abstract PT - Journal Article TT - Valoracion cuantitativa de la rigidez axial, estado funcional y calidad de vida relacionada con la salud en pacientes con enfermedad de Parkinson. PL - Spain TA - Rev Neurol JT - Revista de neurologia JID - 7706841 SB - IM MH - Female MH - Humans MH - Male MH - Middle Aged MH - Muscle Rigidity/*etiology MH - Parkinson Disease/*complications MH - Physical Examination/methods MH - *Quality of Life MH - Thorax EDAT- 2010/07/22 06:00 MHDA- 2010/12/14 06:00 CRDT- 2010/07/22 06:00 PHST- 2010/07/22 06:00 [entrez] PHST- 2010/07/22 06:00 [pubmed] PHST- 2010/12/14 06:00 [medline] AID - rn2009749 [pii] PST - ppublish SO - Rev Neurol. 2010 Aug 16;51(4):193-200.