PMID- 20650668 OWN - NLM STAT- MEDLINE DCOM- 20110107 LR - 20220408 IS - 1532-2165 (Electronic) IS - 1078-5884 (Linking) VI - 40 IP - 6 DP - 2010 Dec TI - The efficacy of a new stimulation technology to increase venous flow and prevent venous stasis. PG - 766-71 LID - 10.1016/j.ejvs.2010.06.019 [doi] AB - OBJECTIVES: Electrical stimulation of calf muscles has been shown to be effective in prevention of DVT. The aim was to determine: (a) dependence of venous blood velocity and ejected volume on the rates of stimulated calf contractions: (b) clinical factors affecting efficacy in healthy individuals. METHODS: The maximum intensity stimulus tolerated was applied to calves of 24 volunteers. In popliteal veins, peak systolic velocities (PSV), ejected volume per individual stimulus (stroke volume SV) and ejected total volume flow per minute (TVF) of expelled blood were determined using ultrasound. Stimulation rates from 2 to 120 beats per minute (bpm) were applied. RESULTS: Mean baseline popliteal PSV was 10 cm/s. For stimulation rates between 2 and 8 bpm, the PSV was 10 times higher and reached 96-105 cm/s. Stroke volume (SV) per individual stimulus decreased in a similar fashion. With increasing rates of stimulation the TVF increased by a factor of 12 times (from 20 ml/min to 240 ml/min). CONCLUSION: Electrical stimulation is an effective method of activating the calf muscle pump. Enhancements of popliteal blood velocity and volume flow are key factors in the prevention of venous stasis and DVT. Further studies are justified to determine the stimulation rates in those with a compromised venous system. CI - Copyright (c) 2010 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved. FAU - Griffin, M AU - Griffin M AD - The Vascular Noninvasive Screening and Diagnostic Centre, 30 Weymouth Street, London W1G 7BS, UK. maurabgriffin@googlemail.com FAU - Nicolaides, A N AU - Nicolaides AN FAU - Bond, D AU - Bond D FAU - Geroulakos, G AU - Geroulakos G FAU - Kalodiki, E AU - Kalodiki E LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20100722 PL - England TA - Eur J Vasc Endovasc Surg JT - European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery JID - 9512728 SB - IM MH - Adolescent MH - Adult MH - Blood Flow Velocity MH - *Electric Stimulation Therapy MH - Female MH - Humans MH - Leg MH - Logistic Models MH - Male MH - Middle Aged MH - *Muscle Contraction MH - Muscle, Skeletal/*blood supply/*innervation MH - Pilot Projects MH - Popliteal Vein/diagnostic imaging/*physiology MH - Reference Values MH - Regional Blood Flow MH - Ultrasonography, Doppler, Color MH - Venous Thrombosis/physiopathology/*prevention & control MH - Young Adult EDAT- 2010/07/24 06:00 MHDA- 2011/01/08 06:00 CRDT- 2010/07/24 06:00 PHST- 2010/04/08 00:00 [received] PHST- 2010/06/20 00:00 [accepted] PHST- 2010/07/24 06:00 [entrez] PHST- 2010/07/24 06:00 [pubmed] PHST- 2011/01/08 06:00 [medline] AID - S1078-5884(10)00401-6 [pii] AID - 10.1016/j.ejvs.2010.06.019 [doi] PST - ppublish SO - Eur J Vasc Endovasc Surg. 2010 Dec;40(6):766-71. doi: 10.1016/j.ejvs.2010.06.019. Epub 2010 Jul 22.