PMID- 20650776
OWN - NLM
STAT- MEDLINE
DCOM- 20130624
LR  - 20100723
IS  - 1673-4254 (Print)
IS  - 1673-4254 (Linking)
VI  - 30
IP  - 7
DP  - 2010 Jul
TI  - [Predictive value of fluorescence in situ hybridization in patients with bladder 
      cancer].
PG  - 1597-9, 1603
AB  - OBJECTIVE: To assess the value of fluorescence in situ hybridization (FISH) in 
      the diagnosis of bladder cancer. METHODS: Urine samples from 100 patients 
      suspected of having bladder cancer were collected before cystoscopy for immediate 
      urine cytology and FISH analysis. The criteria for FISH abnormality were 
      determined by evaluating the urine specimens from 20 subjects without urogenital 
      neoplasm. RESULTS: The overall sensitivity of cytology and FISH was 43.2% and 
      82.4%, and their specificity was 92.3% and 88.5%, with diagnostic concordance 
      rate of 56.0% and 84.0%, respectively. The differences between FISH and cytology 
      showed statistical significance in the sensitivity, diagnostic concordance rate, 
      non-muscle-invasive cancer and primary cancer. CONCLUSION: The sensitivity and 
      efficiency of FISH in the detection of bladder cancer are superior to those of 
      cytology, especially for prophase cancer.
FAU - Shan, Zheng-fei
AU  - Shan ZF
AD  - Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 
      510515, China. shzhf0925@gmail.com
FAU - Zheng, Shao-bin
AU  - Zheng SB
FAU - Wu, Peng
AU  - Wu P
FAU - Tan, Wan-long
AU  - Tan WL
FAU - Zuo, Yi
AU  - Zuo Y
FAU - Zhou, Hai-kuan
AU  - Zhou HK
FAU - Qi, Huan
AU  - Qi H
FAU - Zhang, Peng
AU  - Zhang P
FAU - Peng, Hong-mei
AU  - Peng HM
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - China
TA  - Nan Fang Yi Ke Da Xue Xue Bao
JT  - Nan fang yi ke da xue xue bao = Journal of Southern Medical University
JID - 101266132
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Carcinoma, Transitional Cell/*diagnosis
MH  - Cytodiagnosis
MH  - Female
MH  - Humans
MH  - *In Situ Hybridization, Fluorescence
MH  - Male
MH  - Middle Aged
MH  - Sensitivity and Specificity
MH  - Urinary Bladder Neoplasms/*diagnosis
MH  - Urine/cytology
MH  - Young Adult
EDAT- 2010/07/24 06:00
MHDA- 2013/06/26 06:00
CRDT- 2010/07/24 06:00
PHST- 2010/07/24 06:00 [entrez]
PHST- 2010/07/24 06:00 [pubmed]
PHST- 2013/06/26 06:00 [medline]
PST - ppublish
SO  - Nan Fang Yi Ke Da Xue Xue Bao. 2010 Jul;30(7):1597-9, 1603.