PMID- 20658712
OWN - NLM
STAT- MEDLINE
DCOM- 20100913
LR  - 20100726
IS  - 1107-0625 (Print)
IS  - 1107-0625 (Linking)
VI  - 15
IP  - 2
DP  - 2010 Apr-Jun
TI  - Non-small cell lung cancer: The role of surgery after induction chemo and/or 
      radiotherapy.
PG  - 213-20
AB  - Stages I and II non small cell lung cancer (NSCLC) are primarily treated by 
      anatomic pulmonary resection. Selected patients with stage IIIB disease are still 
      candidates for surgical treatment. Unfortunately, most patients with locally 
      advanced NSCLC don't benefit from surgery alone or even by the combination of 
      chemotherapy and radiotherapy. In order to achieve local and distant disease 
      control, which seems to be the cause of failure of the above mentioned 
      treatments, surgery after induction chemoradiotherapy has been proposed. This 
      approach seems to be the state of the art of therapy for stage IIIB patients 
      improving survival but with eventual increased risk, especially pulmonary and 
      septic complications. This review of previously published studies indicates the 
      important role of this combined treatment in terms of survival and its risks 
      related either to induction treatment or to surgery.
FAU - Stamatelopoulos, A
AU  - Stamatelopoulos A
AD  - Department of Thoracic Surgery, "KAT" General Hospital, Athens, Greece. 
      stanmate11970@yahoo.gr
FAU - Zaragkas, S
AU  - Zaragkas S
FAU - Sofoudis, C
AU  - Sofoudis C
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Cyprus
TA  - J BUON
JT  - Journal of B.U.ON. : official journal of the Balkan Union of Oncology
JID - 100883428
SB  - IM
MH  - Carcinoma, Non-Small-Cell Lung/drug therapy/mortality/radiotherapy/*surgery
MH  - Combined Modality Therapy
MH  - Europe/epidemiology
MH  - Humans
MH  - Lung Neoplasms/drug therapy/mortality/radiotherapy/*surgery
MH  - Neoplasm Staging
MH  - Postoperative Care
MH  - Survival Rate
MH  - Treatment Failure
MH  - Treatment Outcome
MH  - United States/epidemiology
RF  - 72
EDAT- 2010/07/27 06:00
MHDA- 2010/09/14 06:00
CRDT- 2010/07/27 06:00
PHST- 2010/07/27 06:00 [entrez]
PHST- 2010/07/27 06:00 [pubmed]
PHST- 2010/09/14 06:00 [medline]
PST - ppublish
SO  - J BUON. 2010 Apr-Jun;15(2):213-20.