PMID- 20661694 OWN - NLM STAT- MEDLINE DCOM- 20101122 LR - 20211020 IS - 1867-108X (Electronic) IS - 1867-1071 (Linking) VI - 28 IP - 6 DP - 2010 Jul TI - Coronary computed tomography angiography using prospective electrocardiography-gated axial scans with 64-detector computed tomography: evaluation of stair-step artifacts and padding time. PG - 437-45 LID - 10.1007/s11604-010-0448-7 [doi] AB - PURPOSE: We compared stair-step artifacts and radiation dose between prospective electrocardiography (ECG)-gated coronary computed tomography angiography (prospective CCTA) and retrospective CCTA using 64-detector CT and determined the optimal padding time (PT) for prospective CCTA. MATERIALS AND METHODS: We retrospectively evaluated 183 patients [mean heart rate (HR) <65 beats/min, maximum HR instability <5 beats/min] who had undergone CCTA. We scored stair-step artifacts from 1 (severe) to 5 (none) and evaluated the effective dose in 53 patients with retrospective CCTA and 130 with prospective CCTA (PT 200 ms, n = 32; PT 50 ms, n = 98). RESULTS: Mean artifact scores were 4.3 in both retrospective and prospective CCTAs. However, statistically more arteries scored <3 (nonassessable) on prospective CCTA (P < 0.001). Mean scores for prospective CCTA with 200- and 50-ms PT were 4.1 and 4.3, respectively (no significant difference). The radiation dose of prospective CCTA was reduced by 59.1% to 80.7%. CONCLUSION: Prospective CCTA reduces the radiation dose and allows diagnostic imaging in most cases but shows more nonevaluable artifacts than retrospective CCTA. Use of 50-ms instead of 200-ms PT appears to maintain image quality in patients with a mean HR < 65 beats/min and HR instability of <5 beats/min. FAU - Kimura, Fumiko AU - Kimura F AD - Department of Diagnostic Radiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka, 350-1298, Japan. fkimura@saitama-med.ac.jp FAU - Umezawa, Tatsuo AU - Umezawa T FAU - Asano, Tomonari AU - Asano T FAU - Chihara, Ruri AU - Chihara R FAU - Nishi, Naoko AU - Nishi N FAU - Nishimura, Shigeyoshi AU - Nishimura S FAU - Sakai, Fumikazu AU - Sakai F LA - eng PT - Comparative Study PT - Evaluation Study PT - Journal Article DEP - 20100727 PL - Japan TA - Jpn J Radiol JT - Japanese journal of radiology JID - 101490689 RN - 0 (Contrast Media) RN - 4419T9MX03 (Iohexol) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - *Artifacts MH - Contrast Media MH - Coronary Angiography/*methods MH - Coronary Artery Disease/diagnosis MH - Electrocardiography/*methods MH - Female MH - Heart Rate MH - Humans MH - Image Processing, Computer-Assisted/methods MH - Iohexol MH - Male MH - Middle Aged MH - Prospective Studies MH - Radiation Dosage MH - Radiographic Image Enhancement/methods MH - Retrospective Studies MH - Time Factors MH - Tomography, X-Ray Computed/*methods MH - Young Adult EDAT- 2010/07/28 06:00 MHDA- 2010/12/14 06:00 CRDT- 2010/07/28 06:00 PHST- 2010/01/14 00:00 [received] PHST- 2010/03/30 00:00 [accepted] PHST- 2010/07/28 06:00 [entrez] PHST- 2010/07/28 06:00 [pubmed] PHST- 2010/12/14 06:00 [medline] AID - 10.1007/s11604-010-0448-7 [doi] PST - ppublish SO - Jpn J Radiol. 2010 Jul;28(6):437-45. doi: 10.1007/s11604-010-0448-7. Epub 2010 Jul 27.