PMID- 20668196
OWN - NLM
STAT- MEDLINE
DCOM- 20100820
LR  - 20220309
IS  - 1529-2401 (Electronic)
IS  - 0270-6474 (Print)
IS  - 0270-6474 (Linking)
VI  - 30
IP  - 30
DP  - 2010 Jul 28
TI  - Supramodal representations of perceived emotions in the human brain.
PG  - 10127-34
LID - 10.1523/JNEUROSCI.2161-10.2010 [doi]
AB  - Basic emotional states (such as anger, fear, and joy) can be similarly conveyed 
      by the face, the body, and the voice. Are there human brain regions that 
      represent these emotional mental states regardless of the sensory cues from which 
      they are perceived? To address this question, in the present study participants 
      evaluated the intensity of emotions perceived from face movements, body 
      movements, or vocal intonations, while their brain activity was measured with 
      functional magnetic resonance imaging (fMRI). Using multivoxel pattern analysis, 
      we compared the similarity of response patterns across modalities to test for 
      brain regions in which emotion-specific patterns in one modality (e.g., faces) 
      could predict emotion-specific patterns in another modality (e.g., bodies). A 
      whole-brain searchlight analysis revealed modality-independent but emotion 
      category-specific activity patterns in medial prefrontal cortex (MPFC) and left 
      superior temporal sulcus (STS). Multivoxel patterns in these regions contained 
      information about the category of the perceived emotions (anger, disgust, fear, 
      happiness, sadness) across all modality comparisons (face-body, face-voice, 
      body-voice), and independently of the perceived intensity of the emotions. No 
      systematic emotion-related differences were observed in the overall amplitude of 
      activation in MPFC or STS. These results reveal supramodal representations of 
      emotions in high-level brain areas previously implicated in affective processing, 
      mental state attribution, and theory-of-mind. We suggest that MPFC and STS 
      represent perceived emotions at an abstract, modality-independent level, and thus 
      play a key role in the understanding and categorization of others' emotional 
      mental states.
FAU - Peelen, Marius V
AU  - Peelen MV
AD  - Center for Mind/Brain Sciences, University of Trento, Rovereto (TN), Italy. 
      marius.peelen@unitn.it
FAU - Atkinson, Anthony P
AU  - Atkinson AP
FAU - Vuilleumier, Patrik
AU  - Vuilleumier P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Neurosci
JT  - The Journal of neuroscience : the official journal of the Society for 
      Neuroscience
JID - 8102140
RN  - S88TT14065 (Oxygen)
SB  - IM
CIN - J Neurosci. 2010 Dec 8;30(49):16417-8. PMID: 21147980
MH  - Adult
MH  - Analysis of Variance
MH  - Brain/blood supply/*physiology
MH  - *Brain Mapping
MH  - Emotions/*physiology
MH  - Face
MH  - Facial Expression
MH  - Female
MH  - Humans
MH  - Image Processing, Computer-Assisted/methods
MH  - Magnetic Resonance Imaging/methods
MH  - Male
MH  - *Models, Neurological
MH  - Oxygen/blood
MH  - Pattern Recognition, Visual/physiology
MH  - Photic Stimulation/methods
MH  - Reaction Time/physiology
MH  - Young Adult
PMC - PMC6633378
EDAT- 2010/07/30 06:00
MHDA- 2010/08/21 06:00
PMCR- 2011/01/28
CRDT- 2010/07/30 06:00
PHST- 2010/07/30 06:00 [entrez]
PHST- 2010/07/30 06:00 [pubmed]
PHST- 2010/08/21 06:00 [medline]
PHST- 2011/01/28 00:00 [pmc-release]
AID - 30/30/10127 [pii]
AID - 3619089 [pii]
AID - 10.1523/JNEUROSCI.2161-10.2010 [doi]
PST - ppublish
SO  - J Neurosci. 2010 Jul 28;30(30):10127-34. doi: 10.1523/JNEUROSCI.2161-10.2010.