PMID- 20674041 OWN - NLM STAT- MEDLINE DCOM- 20110406 LR - 20211020 IS - 0165-1781 (Print) IS - 1872-7123 (Electronic) IS - 0165-1781 (Linking) VI - 185 IP - 3 DP - 2011 Feb 28 TI - Ecologically valid support for the link between cognitive and psychosocial functioning in bipolar disorder. PG - 353-7 LID - 10.1016/j.psychres.2010.06.010 [doi] AB - Prior research into the link between cognitive and psychosocial functioning in bipolar disorder has examined primarily asymptomatic patients, has measured these domains concurrently, and has failed to establish convergent validity in the assessment of psychosocial dysfunction. The present study examines the relation between cognitive and psychosocial functioning at the time of discharge from hospitalization for acute mood disturbance. We obtained measures of psychosocial functioning that were both close and distant to the time of neuropsychological testing; the former from the discharging psychiatrists, and the latter from reports of formally recognized disability status, determined by persons wholly unrelated to the present research. Sixty-three patients with bipolar I disorder, hospitalized for acute mood disturbance, completed a neuropsychological test battery 24 to 48 h prior to discharge. We compared patients with versus without formal disability status on the Global Assessment of Functioning (GAF) scale and on scores of neuropsychological tests. We also tested associations between GAF scores and cognitive test scores. Results supported the convergent validity in the measurement of psychosocial disability, underscored the robust connection between cognitive and psychosocial impairment, and highlighted the presence of this connection during an important clinical state - time of discharge from psychiatric hospitalization. CI - Copyright (c) 2010 Elsevier Ltd. All rights reserved. FAU - Levy, Boaz AU - Levy B AD - Mental Health Counseling, University of Massachusetts, Boston, MA USA. boaz_levy@hms.harvard.edu FAU - Medina, Anna Marie AU - Medina AM FAU - Hintz, Kathryn AU - Hintz K FAU - Weiss, Roger D AU - Weiss RD LA - eng GR - K24 DA022288-05/DA/NIDA NIH HHS/United States GR - K24 DA022288/DA/NIDA NIH HHS/United States GR - R01 DA15968/DA/NIDA NIH HHS/United States GR - R01 DA015968-05/DA/NIDA NIH HHS/United States GR - R01 DA015968/DA/NIDA NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't DEP - 20100731 PL - Ireland TA - Psychiatry Res JT - Psychiatry research JID - 7911385 SB - IM MH - Adolescent MH - Adult MH - Analysis of Variance MH - Attention MH - Bipolar Disorder/*epidemiology/*psychology MH - Cognition Disorders/*epidemiology/psychology MH - Disability Evaluation MH - *Ecosystem MH - Executive Function MH - Female MH - Humans MH - Male MH - Memory MH - Middle Aged MH - Neuropsychological Tests MH - Psychiatric Status Rating Scales MH - Psychology MH - Reproducibility of Results MH - Young Adult PMC - PMC3146310 MID - NIHMS311901 EDAT- 2010/08/03 06:00 MHDA- 2011/04/07 06:00 PMCR- 2012/02/28 CRDT- 2010/08/03 06:00 PHST- 2010/02/22 00:00 [received] PHST- 2010/05/26 00:00 [revised] PHST- 2010/06/20 00:00 [accepted] PHST- 2010/08/03 06:00 [entrez] PHST- 2010/08/03 06:00 [pubmed] PHST- 2011/04/07 06:00 [medline] PHST- 2012/02/28 00:00 [pmc-release] AID - S0165-1781(10)00352-5 [pii] AID - 10.1016/j.psychres.2010.06.010 [doi] PST - ppublish SO - Psychiatry Res. 2011 Feb 28;185(3):353-7. doi: 10.1016/j.psychres.2010.06.010. Epub 2010 Jul 31.