PMID- 20683103 OWN - NLM STAT- MEDLINE DCOM- 20101216 LR - 20151119 IS - 1735-1502 (Print) IS - 1735-1502 (Linking) VI - 9 IP - 2 DP - 2010 Jun TI - Characterization and stability of specific IgE to white egg's, gliadin's and peanut's proteins among children. PG - 97-102 AB - The aim of the present study was to characterize allergen-specific immunoglobulin E (IgE) among children in Fez region. Eighty one children were recruited from the Hospital University Center of Fez. All of them had completed a questionnaire before taking sera. The sera were used to measure total IgE and specific data to proteins of egg's white (EWP), peanuts (PP) and gliadins (G). In last part, we studied the reactivity of specific IgE to native and to heat- and acid-treated allergens. Allergen-specific IgE measurement indicated more positive values for gliadins (46.9% up to 2IU/ml) than egg white's (29.6%) and peanut's proteins (22.2%). According to predictive values published by Sampson (2001), 14.3% of children are sensitive to egg white's proteins, 4.1% to gliadins and 2.7% to peanut's proteins. The allergenic potential of EWP and gliadins among children were partially diminished by heat and acid treatment. Allergen-specific IgE measurement indicates that children from Fez region are more sensitive to EWP than peanut's proteins and gliadins. Treatments of these food proteins indicated that recognition by children IgE can be reduced by thermal or acid treatment of these allergens. FAU - Ouahidi, Ibtissam AU - Ouahidi I AD - Laboratory of Bioactive Molecules (LMBSF), Faculty of Sciences and Technology, Fez, Morocco. FAU - Elhamsas, Amal El Youbi AU - Elhamsas Ael Y FAU - Bouyahyaoui, Youssef AU - Bouyahyaoui Y FAU - Mernissi, Fatima Zahra AU - Mernissi FZ FAU - Aarab, Lotfi AU - Aarab L LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Iran TA - Iran J Allergy Asthma Immunol JT - Iranian journal of allergy, asthma, and immunology JID - 101146178 RN - 0 (Allergens) RN - 0 (Egg Proteins) RN - 37341-29-0 (Immunoglobulin E) RN - 9007-90-3 (Gliadin) SB - IM MH - Adolescent MH - Allergens/*immunology MH - Arachis/chemistry/*immunology MH - Child MH - Child, Preschool MH - Egg Proteins/*immunology MH - Female MH - Gliadin/chemistry/*immunology MH - Humans MH - Immunoglobulin E/*blood MH - Infant MH - Male EDAT- 2010/08/05 06:00 MHDA- 2010/12/17 06:00 CRDT- 2010/08/05 06:00 PHST- 2010/08/05 06:00 [entrez] PHST- 2010/08/05 06:00 [pubmed] PHST- 2010/12/17 06:00 [medline] AID - 090297102 [pii] PST - ppublish SO - Iran J Allergy Asthma Immunol. 2010 Jun;9(2):97-102.