PMID- 20688252
OWN - NLM
STAT- MEDLINE
DCOM- 20101129
LR  - 20100806
IS  - 1558-3163 (Electronic)
IS  - 0889-857X (Linking)
VI  - 36
IP  - 3
DP  - 2010 Aug
TI  - Outcome measures in ANCA-associated vasculitis.
PG  - 587-607
LID - 10.1016/j.rdc.2010.04.001 [doi]
AB  - The outcome in patients with antineutrophil cytoplasm antibody (ANCA)-associated 
      vasculitis has considerably improved with the use of potent immunosuppression. In 
      the most severe cases, mortality remains an important risk despite aggressive 
      intervention. However, for most patients who survive, quality of survival is 
      affected by morbidity due to low-grade disease activity, episodes of relapse, 
      damage from the effects of disease and its treatment, development of associated 
      comorbidity, and the social and psychological problems of chronic disease. A 
      rational approach to management of patients with ANCA-associated vasculitis 
      requires careful measurement of these different facets of disease, so that 
      treatment is appropriate. This article reviews the development of assessment 
      tools used to quantify disease in vasculitis, which have been extensively used in 
      clinical trials and are also appropriate for use in individual patient care.
CI  - Copyright 2010 Elsevier Inc. All rights reserved.
FAU - Suppiah, Ravi
AU  - Suppiah R
AD  - Department of Rheumatology, Nuffield Orthopaedic Centre, Oxford, OX3 7LD, UK.
FAU - Robson, Joanna
AU  - Robson J
FAU - Luqmani, Raashid
AU  - Luqmani R
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20100615
PL  - United States
TA  - Rheum Dis Clin North Am
JT  - Rheumatic diseases clinics of North America
JID - 8708093
SB  - IM
MH  - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/*diagnosis/*therapy
MH  - Humans
MH  - Recovery of Function
MH  - *Severity of Illness Index
MH  - Treatment Outcome
EDAT- 2010/08/07 06:00
MHDA- 2010/12/14 06:00
CRDT- 2010/08/07 06:00
PHST- 2010/08/07 06:00 [entrez]
PHST- 2010/08/07 06:00 [pubmed]
PHST- 2010/12/14 06:00 [medline]
AID - S0889-857X(10)00037-2 [pii]
AID - 10.1016/j.rdc.2010.04.001 [doi]
PST - ppublish
SO  - Rheum Dis Clin North Am. 2010 Aug;36(3):587-607. doi: 10.1016/j.rdc.2010.04.001. 
      Epub 2010 Jun 15.