PMID- 20692118
OWN - NLM
STAT- MEDLINE
DCOM- 20111213
LR  - 20211203
IS  - 1873-5134 (Electronic)
IS  - 0738-3991 (Print)
IS  - 0738-3991 (Linking)
VI  - 84
IP  - 2
DP  - 2011 Aug
TI  - Patients' reaction to the disclosure of rare dreaded adverse events.
PG  - e1-4
LID - 10.1016/j.pec.2010.07.014 [doi]
AB  - BACKGROUND: Physicians must frequently inform their patients of the risks of 
      rare, but serious, adverse events (AEs). OBJECTIVE: To examine how patients react 
      to the disclosure of rare AEs. METHODS: Outpatients viewed a video of a physician 
      describing a medication associated with a rare AE. Subjects then rated their 
      worry, perceived chance of developing the AE, and willingness to take the 
      medication. RESULTS: Non-White men were more likely to perceive a greater chance 
      of developing the AE compared to White men [Adjusted odds ratio (95% CI) = 3.37 
      (1.09-10.45)]; White women were more likely to be worried [2.00 (0.95-4.24)] and 
      to perceive a greater chance of developing the [6.22 (2.50-15.50)], perceive a 
      greater chance of developing the AE [6.27 (2.43-16.15)], and be less willing to 
      take the medication [0.23 (0.09-0.59)], compared to White men. CONCLUSIONS: 
      Gender and ethnicity influence how patients react to disclosure of rare, but 
      serious, AEs. PRACTICE IMPLICATIONS: An improved understanding of patients' risk 
      perceptions is required to inform the development of best practices to improve 
      risk communication.
CI  - Published by Elsevier Ireland Ltd.
FAU - Fraenkel, Liana
AU  - Fraenkel L
AD  - Section of Rheumatology, Yale University School of Medicine, New Haven, CT 06520, 
      USA. liana.fraenkel@yale.edu
FAU - Peters, Ellen
AU  - Peters E
LA  - eng
GR  - K23 AR048826/AR/NIAMS NIH HHS/United States
GR  - K23 AR048826-05/AR/NIAMS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20100809
PL  - Ireland
TA  - Patient Educ Couns
JT  - Patient education and counseling
JID - 8406280
MH  - Aged
MH  - Communication
MH  - *Disclosure
MH  - *Drug-Related Side Effects and Adverse Reactions
MH  - Ethnicity/psychology
MH  - Female
MH  - Gender Identity
MH  - Humans
MH  - Male
MH  - *Medical Errors
MH  - Middle Aged
MH  - Patient Education as Topic/*methods
MH  - Patients/*psychology
MH  - Risk
MH  - Video Recording
PMC - PMC3033459
MID - NIHMS244942
COIS- Neither author has any conflicts of interests related to the manuscript.
EDAT- 2010/08/10 06:00
MHDA- 2011/12/14 06:00
PMCR- 2012/08/01
CRDT- 2010/08/10 06:00
PHST- 2010/04/29 00:00 [received]
PHST- 2010/06/18 00:00 [revised]
PHST- 2010/07/13 00:00 [accepted]
PHST- 2010/08/10 06:00 [entrez]
PHST- 2010/08/10 06:00 [pubmed]
PHST- 2011/12/14 06:00 [medline]
PHST- 2012/08/01 00:00 [pmc-release]
AID - S0738-3991(10)00415-5 [pii]
AID - 10.1016/j.pec.2010.07.014 [doi]
PST - ppublish
SO  - Patient Educ Couns. 2011 Aug;84(2):e1-4. doi: 10.1016/j.pec.2010.07.014. Epub 
      2010 Aug 9.