PMID- 20695422
OWN - NLM
STAT- MEDLINE
DCOM- 20101210
LR  - 20191210
IS  - 1520-5118 (Electronic)
IS  - 0021-8561 (Linking)
VI  - 58
IP  - 17
DP  - 2010 Sep 8
TI  - Rapid and simultaneous determination of essential minerals and trace elements in 
      human milk by improved flame atomic absorption spectroscopy (FAAS) with microwave 
      digestion.
PG  - 9396-400
LID - 10.1021/jf100940e [doi]
AB  - A method for the simultaneous and economical determination of many trace elements 
      in human milk is developed. Two multi-element hollow cathode lamps (HCLs) were 
      used instead of single-element HCLs to improve the sample throughput of flame 
      atomic absorption spectroscopy (FAAS). The microwave digestion of milk is 
      optimized prior to detection, and the performance characteristics of the improved 
      analysis method are identified. Clinical samples are detected by both FAAS and 
      inductively coupled plasma-optical emission spectroscopy (ICP-OES) for 
      methodology evaluation. Results reveal that the proposed FAAS with multi-element 
      HCLs could determine six essential minerals and trace elements within 15 min. 
      This method provides a linear analytical range of 0.01-10 mg L(-1). For Ca, Cu, 
      Fe, Mg, Mn, and Zn, the limits of determination are 1.5, 3, 1.8, 2.2, 2.1, and 
      1.3 microg L(-1), respectively. The mean relative standard deviations (RSDs) of 
      intra- and interassays are lower than 7%. Excellent operational characteristics 
      of rapidity, simplicity, and economy make the proposed method a promising one for 
      the quantification of trace elements in human milk in clinics of underdeveloped 
      areas.
FAU - Luo, Yang
AU  - Luo Y
AD  - Department of Laboratory Medicine, Southwest Hospital, Third Military Medical 
      University of People's Liberation Army, Chongqing, People's Republic of China.
FAU - Zhang, Bo
AU  - Zhang B
FAU - Chen, Ming
AU  - Chen M
FAU - Wang, Jue
AU  - Wang J
FAU - Zhang, Xue
AU  - Zhang X
FAU - Gao, Wei-Yin
AU  - Gao WY
FAU - Huang, Jun-Fu
AU  - Huang JF
FAU - Fu, Wei-Ling
AU  - Fu WL
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
PL  - United States
TA  - J Agric Food Chem
JT  - Journal of agricultural and food chemistry
JID - 0374755
RN  - 0 (Minerals)
SB  - IM
MH  - Humans
MH  - Limit of Detection
MH  - *Microwaves
MH  - Milk, Human/*chemistry
MH  - Minerals/*analysis
MH  - Reproducibility of Results
MH  - Spectrophotometry, Atomic/*methods
EDAT- 2010/08/11 06:00
MHDA- 2010/12/14 06:00
CRDT- 2010/08/11 06:00
PHST- 2010/08/11 06:00 [entrez]
PHST- 2010/08/11 06:00 [pubmed]
PHST- 2010/12/14 06:00 [medline]
AID - 10.1021/jf100940e [doi]
PST - ppublish
SO  - J Agric Food Chem. 2010 Sep 8;58(17):9396-400. doi: 10.1021/jf100940e.