PMID- 20697188
OWN - NLM
STAT- MEDLINE
DCOM- 20101124
LR  - 20191111
IS  - 1598-9992 (Print)
IS  - 1598-9992 (Linking)
VI  - 55
IP  - 5
DP  - 2010 May
TI  - [Diagnosis of gastroesophageal reflux disease: a systematic review].
PG  - 279-95
AB  - The prevalence of gastoesophageal reflux disease (GERD) has been rapidly 
      increased in Korea during last 20 years. However, there has been no systematic 
      review regarding this disease. The aim of this article was to provide a review of 
      available diagnostic modalities for GERD. This review includes proton pump 
      inhibitor (PPI) test, endoscopy, ambulatory pH monitoring, impedance pH 
      monitoring, and esophageal manometry in order to provide a basis for the 
      currently applicable recommendations in the diagnosis of GERD in Korea. With 
      weekly heartburn or acid regurgitation, the prevalence of GERD has been reported 
      as 3.4% to 7.9%, indicating an increase of GERD in Korea. As the prevalence of 
      Barrett's esophagus has been reported to be low, the screening endoscopy for 
      Barrett's esophagus is not recommended. Several recent meta-analyses re-evaluated 
      the value of the PPI test in patients with typical GERD symptoms and non-cardiac 
      chest pain. That is, the PPI test has been proven to be a sensitive tool for 
      diagnosing GERD in patients with non-cardiac chest pain and in some preliminary 
      trials regarding extraesophageal manifestations of GERD. Ambulatory pH monitoring 
      of the esophagus helps to confirm gastroesophageal reflux in patients with 
      persistent symptoms (both typical and atypical) in the absence of esophageal 
      mucosal damage, especially when a trial of acid suppression has failed. Impedance 
      pH test is useful in refractory reflux patients with primary complaints of 
      typical GERD symptoms, but this value has not been proved in patients with 
      non-cardiac chest pain or extraesophageal symptoms. This systematic review is 
      targeted to establish the strategy of GERD diagnosis, which is essential for the 
      current clinical practice.
FAU - Cho, Yu Kyung
AU  - Cho YK
AD  - Department of Internal Medicine, Seoul Nationsal University College of Medicine, 
      Seoul National University Bundang Hospital, Seongnam, Korea.
FAU - Kim, Gwang Ha
AU  - Kim GH
FAU - Kim, Jeong Hwan
AU  - Kim JH
FAU - Jung, Hwoon-Yong
AU  - Jung HY
FAU - Lee, Joon Seong
AU  - Lee JS
FAU - Kim, Na Young
AU  - Kim NY
CN  - Korean Society of Neurogastroenterology and Motility
LA  - kor
PT  - Journal Article
PT  - Review
PT  - Systematic Review
PL  - Korea (South)
TA  - Korean J Gastroenterol
JT  - The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
JID - 101189416
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Barrett Esophagus/diagnosis
MH  - Esophageal pH Monitoring
MH  - Gastroesophageal Reflux/*diagnosis/epidemiology
MH  - Humans
MH  - Manometry
MH  - Proton Pump Inhibitors/metabolism
MH  - Risk Factors
EDAT- 2010/08/11 06:00
MHDA- 2010/12/14 06:00
CRDT- 2010/08/11 06:00
PHST- 2010/08/11 06:00 [entrez]
PHST- 2010/08/11 06:00 [pubmed]
PHST- 2010/12/14 06:00 [medline]
AID - 201005252 [pii]
AID - 10.4166/kjg.2010.55.5.279 [doi]
PST - ppublish
SO  - Korean J Gastroenterol. 2010 May;55(5):279-95. doi: 10.4166/kjg.2010.55.5.279.