PMID- 20701781
OWN - NLM
STAT- MEDLINE
DCOM- 20101007
LR  - 20211020
IS  - 1743-0003 (Electronic)
IS  - 1743-0003 (Linking)
VI  - 7
DP  - 2010 Aug 11
TI  - Assessing motor deficits in compressive neuropathy using quantitative 
      electromyography.
PG  - 39
LID - 10.1186/1743-0003-7-39 [doi]
AB  - BACKGROUND: Studying the changes that occur in motor unit potential trains 
      (MUPTs) may provide insight into the extent of motor unit loss and neural 
      re-organization resulting from nerve compression injury. The purpose of this 
      study was to determine the feasibility of using decomposition-based quantitative 
      electromyography (DQEMG) to study the pathophysiological changes associated with 
      compression neuropathy. METHODS: The model used to examine compression neuropathy 
      was carpal tunnel syndrome (CTS) due to its high prevalence and ease of 
      diagnosis. Surface and concentric needle electromyography data were acquired 
      simultaneously from the abductor pollicis brevis muscle in six individuals with 
      severe CTS, eight individuals with mild CTS and nine healthy control subjects. 
      DQEMG was used to detect intramuscular MUPTs during constant-intensity 
      contractions and to estimate parameters associated with the surface- and 
      needle-detected motor unit potentials (SMUPs and MUPs, respectively). MUP 
      morphology and stability, SMUP morphology and motor unit number estimates (MUNEs) 
      were compared among the groups using Kruskal-Wallis tests. RESULTS: The severe 
      CTS group had larger amplitude and longer duration MUPs and smaller MUNEs than 
      the mild CTS and control groups, suggesting that the individuals with severe CTS 
      had motor unit loss with subsequent collateral reinnervation, and that DQEMG 
      using a constant-intensity protocol was sensitive to these changes. SMUP 
      morphology and MUP complexity and stability did not significantly differ among 
      the groups. CONCLUSIONS: These results provide evidence that MUP amplitude 
      parameters and MUNEs obtained using DQEMG, may be a valuable tool to investigate 
      pathophysiological changes in muscles affected by compressive motor neuropathy to 
      augment information obtained from nerve conduction studies. Although there were 
      trends in many of these measures, in this study, MUP complexity and stability and 
      SMUP parameters were, of limited value.
FAU - Nashed, Joseph
AU  - Nashed J
AD  - School of Rehabilitation Therapy, Queen's University, Kingston, Ontario, Canada.
FAU - Hamilton-Wright, Andrew
AU  - Hamilton-Wright A
FAU - Stashuk, Daniel W
AU  - Stashuk DW
FAU - Faris, Matthew
AU  - Faris M
FAU - McLean, Linda
AU  - McLean L
LA  - eng
PT  - Journal Article
DEP - 20100811
PL  - England
TA  - J Neuroeng Rehabil
JT  - Journal of neuroengineering and rehabilitation
JID - 101232233
SB  - IM
MH  - Adult
MH  - Carpal Tunnel Syndrome/*diagnosis/*physiopathology
MH  - Case-Control Studies
MH  - Data Interpretation, Statistical
MH  - Electromyography/*methods
MH  - *Evoked Potentials, Motor
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Muscle Contraction/physiology
MH  - Muscle, Skeletal/*physiopathology
MH  - Neural Conduction
MH  - Severity of Illness Index
MH  - Signal Processing, Computer-Assisted
MH  - Time Factors
PMC - PMC2928769
EDAT- 2010/08/13 06:00
MHDA- 2010/10/12 06:00
PMCR- 2010/08/11
CRDT- 2010/08/13 06:00
PHST- 2009/12/22 00:00 [received]
PHST- 2010/08/11 00:00 [accepted]
PHST- 2010/08/13 06:00 [entrez]
PHST- 2010/08/13 06:00 [pubmed]
PHST- 2010/10/12 06:00 [medline]
PHST- 2010/08/11 00:00 [pmc-release]
AID - 1743-0003-7-39 [pii]
AID - 10.1186/1743-0003-7-39 [doi]
PST - epublish
SO  - J Neuroeng Rehabil. 2010 Aug 11;7:39. doi: 10.1186/1743-0003-7-39.