PMID- 20717554
OWN - NLM
STAT- MEDLINE
DCOM- 20101208
LR  - 20220408
IS  - 1660-4601 (Electronic)
IS  - 1661-7827 (Print)
IS  - 1660-4601 (Linking)
VI  - 7
IP  - 7
DP  - 2010 Jul
TI  - Endocrine disruptors and obesity: an examination of selected persistent organic 
      pollutants in the NHANES 1999-2002 data.
PG  - 2988-3005
LID - 10.3390/ijerph7072988 [doi]
AB  - Recent evidence suggests that endocrine disrupting chemicals (EDCs) may cause 
      perturbations in endogenous hormonal regulation that predispose to weight gain. 
      Using data from NHANES (1999-2002), we investigated the association between body 
      mass index (BMI), waist circumference (WC) and selected persistent organic 
      pollutants (POPs) via multiple linear regressions. Consistent interaction was 
      found between gender, ln oxychlordane and ln p,p' DDT. Also, we found an 
      association between WC and ln oxychlordane and ln hpcdd in subjects with 
      detectable levels of POPs, whereas an association between WC and ln p,p' DDT was 
      observed in all subjects. Furthermore, ln Ocdd showed an increase with higher WC 
      and BMI, whereas, ln trans-nonachlor decreased with higher BMI. Hence, BMI and WC 
      are associated with POPs levels, making the chemicals plausible contributors to 
      the obesity epidemic.
FAU - Elobeid, Mai A
AU  - Elobeid MA
AD  - Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL 
      35294, USA. maielobeid@gmail.com
FAU - Padilla, Miguel A
AU  - Padilla MA
FAU - Brock, David W
AU  - Brock DW
FAU - Ruden, Douglas M
AU  - Ruden DM
FAU - Allison, David B
AU  - Allison DB
LA  - eng
GR  - R01AR052658/AR/NIAMS NIH HHS/United States
GR  - T32HL007457/HL/NHLBI NIH HHS/United States
GR  - R01 CA105349/CA/NCI NIH HHS/United States
GR  - R01 ES012933/ES/NIEHS NIH HHS/United States
GR  - P30 DK056336/DK/NIDDK NIH HHS/United States
GR  - P30 ES06639/ES/NIEHS NIH HHS/United States
GR  - T32 HL007457/HL/NHLBI NIH HHS/United States
GR  - R01 AR052658/AR/NIAMS NIH HHS/United States
GR  - P30 ES006639/ES/NIEHS NIH HHS/United States
GR  - P30DK056336/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20100723
PL  - Switzerland
TA  - Int J Environ Res Public Health
JT  - International journal of environmental research and public health
JID - 101238455
RN  - 0 (Dioxins)
RN  - 0 (Endocrine Disruptors)
RN  - 0 (Hydrocarbons, Chlorinated)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Body Mass Index
MH  - Child
MH  - Cross-Sectional Studies
MH  - Dioxins/*adverse effects
MH  - Endocrine Disruptors/*adverse effects
MH  - Female
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*adverse effects
MH  - Male
MH  - Nutrition Surveys
MH  - Obesity/*etiology
MH  - Public Health
MH  - Regression Analysis
MH  - United States
MH  - Waist-Hip Ratio
MH  - Young Adult
PMC - PMC2922741
OTO - NOTNLM
OT  - Obesity
OT  - endocrine disruptors
OT  - persistent organic pollutants
OT  - public health
OT  - waist circumference
EDAT- 2010/08/19 06:00
MHDA- 2010/12/14 06:00
PMCR- 2010/07/01
CRDT- 2010/08/19 06:00
PHST- 2010/06/16 00:00 [received]
PHST- 2010/07/16 00:00 [revised]
PHST- 2010/07/19 00:00 [accepted]
PHST- 2010/08/19 06:00 [entrez]
PHST- 2010/08/19 06:00 [pubmed]
PHST- 2010/12/14 06:00 [medline]
PHST- 2010/07/01 00:00 [pmc-release]
AID - ijerph7072988 [pii]
AID - ijerph-07-02988 [pii]
AID - 10.3390/ijerph7072988 [doi]
PST - ppublish
SO  - Int J Environ Res Public Health. 2010 Jul;7(7):2988-3005. doi: 
      10.3390/ijerph7072988. Epub 2010 Jul 23.