PMID- 20720366 OWN - NLM STAT- MEDLINE DCOM- 20110519 LR - 20190606 IS - 1349-7235 (Electronic) IS - 0918-2918 (Linking) VI - 49 IP - 16 DP - 2010 TI - Pulmonary Mycobacterium parascrofulaceum infection as an immune reconstitution inflammatory syndrome in an AIDS patient. PG - 1817-21 AB - Nontuberculous mycobacterial (NTM) infection in HIV (human immunodeficiency virus)-infected patients who have started highly active antiretroviral therapy (HAART) is well known to be one scenario of immune reconstitution inflammatory syndrome (IRIS). We encountered the first case in Japan of an HIV-infected patient with pulmonary Mycobacterium parascrofulaceum infection as IRIS. A 34 year-old man with acquired immunodeficiency syndrome (AIDS) was receiving highly active antiretroviral therapy. Lymphadenopathy was observed at the left pulmonary hilum. IRIS was suspected and thoracoscopic surgery was performed to diagnose the cause of lymphadenopathy. Granulomas were observed histologically, and M. parascrofulaceum was cultured. This organism was susceptible to Clarithromycin, rifampicin and levofloxacin. After the operation and without treatment, recurrence of M. parascrofulaceum infection was not observed. M. parascrofulaceum was isolated from several clinical specimens for the first time in 2004. To date, only five cases have been reported. FAU - Teruya, Hiromitsu AU - Teruya H AD - Department of Medicine and Therapeutics, Control and Prevention of Infectious Diseases, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan. h043331@med.u-ryukyu.ac.jp FAU - Tateyama, Masao AU - Tateyama M FAU - Hibiya, Kenji AU - Hibiya K FAU - Tamaki, Yuichiro AU - Tamaki Y FAU - Haranaga, Shusaku AU - Haranaga S FAU - Nakamura, Hideta AU - Nakamura H FAU - Tasato, Daisuke AU - Tasato D FAU - Higa, Futoshi AU - Higa F FAU - Hirayasu, Tsuneo AU - Hirayasu T FAU - Furugen, Tomonori AU - Furugen T FAU - Kato, Seiya AU - Kato S FAU - Kazumi, Yuko AU - Kazumi Y FAU - Maeda, Shinji AU - Maeda S FAU - Fujita, Jiro AU - Fujita J LA - eng PT - Case Reports PT - Journal Article PT - Review DEP - 20100813 PL - Japan TA - Intern Med JT - Internal medicine (Tokyo, Japan) JID - 9204241 SB - IM MH - AIDS-Related Opportunistic Infections/*complications/diagnosis MH - Acquired Immunodeficiency Syndrome/complications/*diagnosis MH - Adult MH - Antiretroviral Therapy, Highly Active/adverse effects MH - Humans MH - Immune Reconstitution Inflammatory Syndrome/complications/*diagnosis MH - Male MH - *Mycobacterium MH - Mycobacterium Infections/complications/*diagnosis MH - Respiratory Tract Infections/complications/*diagnosis EDAT- 2010/08/20 06:00 MHDA- 2011/05/20 06:00 CRDT- 2010/08/20 06:00 PHST- 2010/08/20 06:00 [entrez] PHST- 2010/08/20 06:00 [pubmed] PHST- 2011/05/20 06:00 [medline] AID - JST.JSTAGE/internalmedicine/49.3616 [pii] AID - 10.2169/internalmedicine.49.3616 [doi] PST - ppublish SO - Intern Med. 2010;49(16):1817-21. doi: 10.2169/internalmedicine.49.3616. Epub 2010 Aug 13.