PMID- 20725707
OWN - NLM
STAT- MEDLINE
DCOM- 20110228
LR  - 20211020
IS  - 1432-1289 (Electronic)
IS  - 0020-9554 (Linking)
VI  - 51
IP  - 10
DP  - 2010 Oct
TI  - [Registries of myocardial infarction in Germany. Consequences for drug therapy of 
      patients with acute ST elevation myocardial infarction].
PG  - 1324-7, 1329
LID - 10.1007/s00108-010-2662-x [doi]
AB  - Current national and international guidelines for patients with ST elevation 
      myocardial infarction (STEMI) are mainly based on the results of randomised 
      clinical trials. However, it is well perceived that patients in such trials often 
      represent a low risk population. Therefore the results of randomised clinical 
      trials are not necessarily applicable to patients in clinical practice. This gap 
      can be filled by prospective registries. Since the early nineties a number of 
      prospective large registries in patients with STEMI have been performed in 
      Germany. It could be shown that guideline adherent acute therapies and secondary 
      prevention therapies were associated with an improvement in inhospital and 
      mid-term outcomes. The benefit of guideline adherent therapy observed was 
      especially high in patients with higher baseline risk. Registries are not able to 
      replace randomised clinical trials, but can help to test if the results of these 
      trials are comprehensible in clinical practice. Therefore prospective STEMI 
      registries are an important part of clinical research to optimize therapies and 
      improve outcome in patients with STEMI.
FAU - Zeymer, U
AU  - Zeymer U
AD  - Medizinische Klinik B, Klinikum der Stadt Ludwigshafen gGmbH, Ludwigshafen, 
      Deutschland. Uwe.Zeymer@t-online.de
FAU - Zahn, R
AU  - Zahn R
FAU - Senges, J
AU  - Senges J
FAU - Gitt, A
AU  - Gitt A
LA  - ger
PT  - Journal Article
TT  - Herzinfarktregister in Deutschland. Konsequenzen fur die Arzneimitteltherapie bei 
      Patienten mit akutem ST-Strecken-Hebungsinfarkt.
PL  - Germany
TA  - Internist (Berl)
JT  - Der Internist
JID - 0264620
RN  - 0 (Adrenergic beta-Antagonists)
RN  - 0 (Angiotensin Receptor Antagonists)
RN  - 0 (Angiotensin-Converting Enzyme Inhibitors)
RN  - 0 (Hydroxymethylglutaryl-CoA Reductase Inhibitors)
RN  - 0 (Platelet Aggregation Inhibitors)
RN  - A74586SNO7 (Clopidogrel)
RN  - OM90ZUW7M1 (Ticlopidine)
RN  - R16CO5Y76E (Aspirin)
SB  - IM
MH  - Adrenergic beta-Antagonists/therapeutic use
MH  - Aged
MH  - Aged, 80 and over
MH  - Angina, Unstable/drug therapy/mortality
MH  - Angioplasty, Balloon, Coronary
MH  - Angiotensin Receptor Antagonists/therapeutic use
MH  - Angiotensin-Converting Enzyme Inhibitors/therapeutic use
MH  - Aspirin/therapeutic use
MH  - Clopidogrel
MH  - Coronary Restenosis/mortality/prevention & control
MH  - Drug Therapy, Combination
MH  - *Electrocardiography
MH  - *Evidence-Based Medicine
MH  - Germany
MH  - Guideline Adherence
MH  - Hospital Mortality
MH  - Humans
MH  - Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use
MH  - Middle Aged
MH  - Myocardial Infarction/*drug therapy/mortality
MH  - Platelet Aggregation Inhibitors/therapeutic use
MH  - Prospective Studies
MH  - Randomized Controlled Trials as Topic
MH  - *Registries
MH  - Secondary Prevention
MH  - Survival Analysis
MH  - Thrombolytic Therapy
MH  - Ticlopidine/analogs & derivatives/therapeutic use
MH  - Treatment Outcome
EDAT- 2010/08/21 06:00
MHDA- 2011/03/01 06:00
CRDT- 2010/08/21 06:00
PHST- 2010/08/21 06:00 [entrez]
PHST- 2010/08/21 06:00 [pubmed]
PHST- 2011/03/01 06:00 [medline]
AID - 10.1007/s00108-010-2662-x [doi]
PST - ppublish
SO  - Internist (Berl). 2010 Oct;51(10):1324-7, 1329. doi: 10.1007/s00108-010-2662-x.