PMID- 20726378 OWN - NLM STAT- MEDLINE DCOM- 20100902 LR - 20100823 IS - 0888-5109 (Print) IS - 0888-5109 (Linking) VI - 25 Suppl B DP - 2010 Jun TI - Prediabetes in a nursing facility patient with renal insufficiency. PG - 11-8 AB - OBJECTIVES: Prediabetes encompasses a variety of abnormalities, including impaired fasting glucose, impaired glucose tolerance, and metabolic syndrome. Prediabetes also increases the risk of developing type 2 diabetes mellitus (T2DM) by 3- to 10-fold, but the complications associated with hyperglycemia begin early in the patient's progression from normal glucose levels to diabetes. Early identification and treatment of prediabetes has the potential to reduce or delay progression to overt diabetes, to preempt related cardiovascular and microvascular disease, and to significantly improve morbidity and mortality. This clinical review provides a vehicle to examine management of prediabetes in patients 65 years of age and older, including diagnostic criteria and recommendations for management. DATA SOURCES: Live symposium presentation based on clinical practice and research, medical literature, and studies published between May 1999 and March 2010 on managing diabetes in older adults, government statistics, and medical society guidelines. CONCLUSIONS: Effective prediabetes management is important to reducing the risk of progression to T2DM. Recommended first-line therapy is lifestyle modification that may include exercise, nutritional therapy, and weight loss. Pharmacological therapies, when indicated, can aid in improving glucose, blood pressure, and lipid parameters in this patient subgroup. FAU - Shane-McWhorter, Laura AU - Shane-McWhorter L AD - Department of Pharmacotherapy, University of Utah College of Pharmacy, Salt Lake City, Utah 84112, USA. lmcwhorter@pharm.utah.edu LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - Consult Pharm JT - The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists JID - 9013983 RN - 0 (Blood Glucose) RN - 0 (Lipids) SB - IM MH - Aged MH - Blood Glucose/drug effects MH - Blood Pressure/drug effects MH - Diabetes Mellitus, Type 2/etiology/*prevention & control MH - Disease Progression MH - Humans MH - Life Style MH - Lipids/blood MH - Male MH - Mass Screening/methods MH - Nursing Homes MH - Prediabetic State/complications/diagnosis/*therapy MH - Renal Insufficiency/*complications MH - Risk Factors EDAT- 2010/08/24 06:00 MHDA- 2010/09/03 06:00 CRDT- 2010/08/24 06:00 PHST- 2010/08/24 06:00 [entrez] PHST- 2010/08/24 06:00 [pubmed] PHST- 2010/09/03 06:00 [medline] PST - ppublish SO - Consult Pharm. 2010 Jun;25 Suppl B:11-8.