PMID- 20728918
OWN - NLM
STAT- MEDLINE
DCOM- 20101029
LR  - 20221020
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 408
IP  - 22
DP  - 2010 Oct 15
TI  - Environmental contaminants and human health in the Canadian Arctic.
PG  - 5165-234
LID - 10.1016/j.scitotenv.2010.04.059 [doi]
AB  - The third Canadian Arctic Human Health Assessment conducted under the Canadian 
      Northern Contaminants Program (NCP), in association with the circumpolar Arctic 
      Monitoring and Assessment Programme (AMAP), addresses concerns about possible 
      adverse health effects in individuals exposed to environmental contaminants 
      through a diet containing country foods. The objectives here are to: 1) provide 
      data on changes in human contaminant concentrations and exposure among Canadian 
      Arctic peoples; 2) identify new contaminants of concern; 3) discuss possible 
      health effects; 4) outline risk communication about contaminants in country food; 
      and 5) identify knowledge gaps for future contaminant research and monitoring. 
      The nutritional and cultural benefits of country foods are substantial; however, 
      some dietary studies suggest declines in the amount of country foods being 
      consumed. Significant declines were found for most contaminants in maternal blood 
      over the last 10 years within all three Arctic regions studied. Inuit continue to 
      have the highest levels of almost all persistent organic pollutants (POPs) and 
      metals among the ethnic groups studied. A greater proportion of people in the 
      East exceed Health Canada's guidelines for PCBs and mercury, although the 
      proportion of mothers exceeding these guidelines has decreased since the previous 
      assessment. Further monitoring and research are required to assess trends and 
      health effects of emerging contaminants. Infant development studies have shown 
      possible subtle effects of prenatal exposure to heavy metals and some POPs on 
      immune system function and neurodevelopment. New data suggest important 
      beneficial effects on brain development for Inuit infants from some country food 
      nutrients. The most successful risk communication processes balance the risks and 
      benefits of a diet of country food through input from a variety of regional 
      experts and the community, to incorporate the many socio-cultural and economic 
      factors to arrive at a risk management decision that will be the most beneficial 
      in Arctic communities.
CI  - Crown Copyright (c) 2010. Published by Elsevier B.V. All rights reserved.
FAU - Donaldson, S G
AU  - Donaldson SG
AD  - Chemicals Surveillance Bureau, HECSB, Health Canada, 269 Laurier Ave West, 
      Ottawa, ON, Canada K1A 0K9.
FAU - Van Oostdam, J
AU  - Van Oostdam J
FAU - Tikhonov, C
AU  - Tikhonov C
FAU - Feeley, M
AU  - Feeley M
FAU - Armstrong, B
AU  - Armstrong B
FAU - Ayotte, P
AU  - Ayotte P
FAU - Boucher, O
AU  - Boucher O
FAU - Bowers, W
AU  - Bowers W
FAU - Chan, L
AU  - Chan L
FAU - Dallaire, F
AU  - Dallaire F
FAU - Dallaire, R
AU  - Dallaire R
FAU - Dewailly, E
AU  - Dewailly E
FAU - Edwards, J
AU  - Edwards J
FAU - Egeland, G M
AU  - Egeland GM
FAU - Fontaine, J
AU  - Fontaine J
FAU - Furgal, C
AU  - Furgal C
FAU - Leech, T
AU  - Leech T
FAU - Loring, E
AU  - Loring E
FAU - Muckle, G
AU  - Muckle G
FAU - Nancarrow, T
AU  - Nancarrow T
FAU - Pereg, D
AU  - Pereg D
FAU - Plusquellec, P
AU  - Plusquellec P
FAU - Potyrala, M
AU  - Potyrala M
FAU - Receveur, O
AU  - Receveur O
FAU - Shearer, R G
AU  - Shearer RG
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20100821
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Environmental Pollutants)
SB  - IM
EIN - Sci Total Environ. 2012 Aug 1;431:437-8
MH  - Adolescent
MH  - Adult
MH  - Arctic Regions/epidemiology
MH  - Canada/epidemiology
MH  - Climate Change
MH  - Diet/statistics & numerical data
MH  - Disease
MH  - Environmental Exposure/statistics & numerical data
MH  - Environmental Pollutants/*analysis
MH  - Environmental Pollution/*statistics & numerical data
MH  - Female
MH  - *Health Status
MH  - Humans
MH  - Indians, North American
MH  - Male
MH  - Risk Assessment
MH  - Risk Factors
MH  - Young Adult
EDAT- 2010/08/24 06:00
MHDA- 2010/10/30 06:00
CRDT- 2010/08/24 06:00
PHST- 2009/12/16 00:00 [received]
PHST- 2010/04/23 00:00 [revised]
PHST- 2010/04/29 00:00 [accepted]
PHST- 2010/08/24 06:00 [entrez]
PHST- 2010/08/24 06:00 [pubmed]
PHST- 2010/10/30 06:00 [medline]
AID - S0048-9697(10)00455-9 [pii]
AID - 10.1016/j.scitotenv.2010.04.059 [doi]
PST - ppublish
SO  - Sci Total Environ. 2010 Oct 15;408(22):5165-234. doi: 
      10.1016/j.scitotenv.2010.04.059. Epub 2010 Aug 21.