PMID- 20731047 OWN - NLM STAT- MEDLINE DCOM- 20110128 LR - 20220327 IS - 1008-9292 (Print) IS - 1008-9292 (Linking) VI - 39 IP - 4 DP - 2010 Jul TI - [Research progress on expression and function of Toll-like receptors in dendritic cells]. PG - 436-41 AB - Dendritic cells (DCs), the most potent antigen-presenting cells, recognize pathogen by Toll-like receptors (TLRs) and serve as the bridge between the innate and the adaptive immune responses. TLRs-mediated signal transduction plays a crucial role in the functional maturation of DCs. This review summarizes the research progress on the expression and function of TLRs in DCs. FAU - Guo, Jia AU - Guo J AD - Department of Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China. FAU - Pan, Jian-ping AU - Pan JP LA - chi PT - English Abstract PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review PL - China TA - Zhejiang Da Xue Xue Bao Yi Xue Ban JT - Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences JID - 100927946 RN - 0 (Toll-Like Receptors) SB - IM MH - Dendritic Cells/*immunology/metabolism MH - Humans MH - Immunity, Innate MH - Signal Transduction MH - Toll-Like Receptors/*metabolism/*physiology EDAT- 2010/08/24 06:00 MHDA- 2011/02/01 06:00 CRDT- 2010/08/24 06:00 PHST- 2010/08/24 06:00 [entrez] PHST- 2010/08/24 06:00 [pubmed] PHST- 2011/02/01 06:00 [medline] AID - 10.3785/j.issn.1008-9292.2010.04.018 [doi] PST - ppublish SO - Zhejiang Da Xue Xue Bao Yi Xue Ban. 2010 Jul;39(4):436-41. doi: 10.3785/j.issn.1008-9292.2010.04.018.