PMID- 20738320
OWN - NLM
STAT- MEDLINE
DCOM- 20110524
LR  - 20131121
IS  - 1365-2230 (Electronic)
IS  - 0307-6938 (Linking)
VI  - 36
IP  - 3
DP  - 2011 Apr
TI  - Drug-induced subacute cutaneous lupus erythematosus associated with omeprazole.
PG  - 281-3
LID - 10.1111/j.1365-2230.2010.03926.x [doi]
AB  - Subacute cutaneous lupus erythematosus (SCLE) is characterized by annular scaly 
      erythematous plaques in a photosensitive distribution, and the presence of 
      anti-Ro (SSA) and/or anti-La (SSB) antibodies. Most cases of SCLE are idiopathic, 
      but occasional cases may be drug-induced or associated with a hereditary 
      deficiency of complement components. We report two cases of drug-induced SCLE 
      precipitated by the proton pump inhibitor, omeprazole. Drug-induced disease 
      should be considered in all atypical or extensive cases of SCLE, especially in 
      elderly patients.
CI  - (c) The Author(s). CED (c) 2010 British Association of Dermatologists.
FAU - Toms-Whittle, L M
AU  - Toms-Whittle LM
AD  - Department of Dermatology, Great Western Hospital NHS Foundation Trust, Swindon, 
      Wiltshire, UK.
FAU - John, L H
AU  - John LH
FAU - Buckley, D A
AU  - Buckley DA
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20100825
PL  - England
TA  - Clin Exp Dermatol
JT  - Clinical and experimental dermatology
JID - 7606847
RN  - 0 (Anti-Ulcer Agents)
RN  - 0 (Proton Pump Inhibitors)
RN  - KG60484QX9 (Omeprazole)
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Anti-Ulcer Agents/*adverse effects
MH  - Drug Eruptions/*etiology/pathology
MH  - Female
MH  - Humans
MH  - Lupus Erythematosus, Cutaneous/*chemically induced/pathology
MH  - Omeprazole/*adverse effects
MH  - Proton Pump Inhibitors/adverse effects
EDAT- 2010/08/27 06:00
MHDA- 2011/05/25 06:00
CRDT- 2010/08/27 06:00
PHST- 2010/08/27 06:00 [entrez]
PHST- 2010/08/27 06:00 [pubmed]
PHST- 2011/05/25 06:00 [medline]
AID - CED3926 [pii]
AID - 10.1111/j.1365-2230.2010.03926.x [doi]
PST - ppublish
SO  - Clin Exp Dermatol. 2011 Apr;36(3):281-3. doi: 10.1111/j.1365-2230.2010.03926.x. 
      Epub 2010 Aug 25.