PMID- 20738729
OWN - NLM
STAT- MEDLINE
DCOM- 20110607
LR  - 20121115
IS  - 1540-8183 (Electronic)
IS  - 0896-4327 (Linking)
VI  - 24
IP  - 1
DP  - 2011 Feb
TI  - Balloon aortic valvuloplasty for aortic stenosis using a novel percutaneous 
      dilation catheter and power injector.
PG  - 92-8
LID - 10.1111/j.1540-8183.2010.00594.x [doi]
AB  - Calcific aortic stenosis is the most common valvular heart disease in the Western 
      world. Although definitive treatment is valve replacement, many patients are not 
      replacement candidates due to high surgical risk from older age and comorbid 
      illness or lack of desire for a surgical or replacement procedure. Percutaneous 
      balloon aortic valvuloplasty (BAV) is an option for palliative treatment in 
      nonsurgical patients, although this procedure is complicated during the immediate 
      postprocedure period by bleeding requiring transfusion for about 1 in 5 patients 
      and subsequent restenosis. This report describes BAV using a smaller profile 
      balloon designed to withstand higher pressures, rapidly inflated with a power 
      injector. Twenty consecutive high-risk patients with severe aortic stenosis were 
      treated. In all cases, New York Heart Association (NYHA) class improved from IV 
      before BAV to I or II at 30 days follow-up. Six-month posttreatment follow-up 
      data were available for 19 of 20 patients: 15 patients were either NYHA class I 
      or II, 1 patient was class III, and 3 deaths occurred unrelated to aortic 
      stenosis. One patient was lost to follow-up. Average systolic gradient 
      peak-to-peak pressure decreased by 40.0% (range 18.0-70.0%) and mean gradient 
      decreased by 30.0% (range 13.7-70.8%). Aortic valve area increased from 0.59 +/- 
      0.16 cm(2) to 0.92 +/- 0.23 cm(2), representing a mean increase of 30.0% (range 
      7.8%-58.2%). There were no significant bleeding complications. The only 
      procedural complication was a single case of pericardial tamponade. There were no 
      other complications during the first 24 hours post-BAV. These data support that 
      the reported BAV technique may offer an effective alternative for patients with 
      severe aortic stenosis who are not surgical candidates or prefer to avoid aortic 
      valve replacement.
CI  - (c)2010, Wiley Periodicals, Inc.
FAU - Eles, Gustav R
AU  - Eles GR
AD  - Division of Cardiology, Allegheny General Hospital, Pittsburgh, Pennsylvania 
      15212, USA. drgeles@aol.com
FAU - Fisher, Don L
AU  - Fisher DL
FAU - Khalil, Ramzi
AU  - Khalil R
FAU - Dajani, Zuhdi
AU  - Dajani Z
FAU - Spotti, Jennifer P
AU  - Spotti JP
FAU - Lasorda, David
AU  - Lasorda D
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20100825
PL  - United States
TA  - J Interv Cardiol
JT  - Journal of interventional cardiology
JID - 8907826
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortic Valve/*pathology
MH  - Aortic Valve Stenosis/*therapy
MH  - Calcinosis/*therapy
MH  - Cardiac Surgical Procedures
MH  - Catheterization/*instrumentation/methods
MH  - Female
MH  - Health Status Indicators
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Severity of Illness Index
MH  - Systole
EDAT- 2010/08/27 06:00
MHDA- 2011/06/08 06:00
CRDT- 2010/08/27 06:00
PHST- 2010/08/27 06:00 [entrez]
PHST- 2010/08/27 06:00 [pubmed]
PHST- 2011/06/08 06:00 [medline]
AID - JOIC594 [pii]
AID - 10.1111/j.1540-8183.2010.00594.x [doi]
PST - ppublish
SO  - J Interv Cardiol. 2011 Feb;24(1):92-8. doi: 10.1111/j.1540-8183.2010.00594.x. 
      Epub 2010 Aug 25.