PMID- 20797620 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20100920 LR - 20100827 IS - 1097-4164 (Electronic) IS - 1097-2765 (Linking) VI - 39 IP - 4 DP - 2010 Aug 27 TI - GTP: gatekeeper for autophagy. PG - 485-6 LID - 10.1016/j.molcel.2010.08.005 [doi] AB - Chaperone-mediated autophagy (CMA) is involved in cellular quality control, and in the response to stress, deterioration in CMA contributes to the aging phenotype and to various disorders. The paper by Bandyopadhyay et al. in this issue of Molecular Cell demonstrates the role of GTP binding by elongation factor 1 alpha (EF1alpha) in regulating the lysosomal uptake of CMA substrates. CI - Copyright (c) 2010 Elsevier Inc. All rights reserved. FAU - Beau, Isabelle AU - Beau I AD - INSERM UMR984, Universite Paris-Sud 11, Faculte de Pharmacie, 5 rue Jean-Baptiste Clement, 92296 Chatenay-Malabry, France. FAU - Codogno, Patrice AU - Codogno P LA - eng PT - Comment PT - Journal Article PL - United States TA - Mol Cell JT - Molecular cell JID - 9802571 CON - Mol Cell. 2010 Aug 27;39(4):535-47. PMID: 20797626 EDAT- 2010/08/28 06:00 MHDA- 2010/08/28 06:01 CRDT- 2010/08/28 06:00 PHST- 2010/08/28 06:00 [entrez] PHST- 2010/08/28 06:00 [pubmed] PHST- 2010/08/28 06:01 [medline] AID - S1097-2765(10)00615-5 [pii] AID - 10.1016/j.molcel.2010.08.005 [doi] PST - ppublish SO - Mol Cell. 2010 Aug 27;39(4):485-6. doi: 10.1016/j.molcel.2010.08.005.