PMID- 20799353 OWN - NLM STAT- MEDLINE DCOM- 20110209 LR - 20171116 IS - 1522-726X (Electronic) IS - 1522-1946 (Linking) VI - 76 IP - 5 DP - 2010 Nov 1 TI - Alcohol septal ablation after myomectomy failure solutions for unusual cases. PG - 719-23 LID - 10.1002/ccd.22539 [doi] AB - We report an eight-year-old child presented with classical features of hypertrophic obstructive cardiomyopathy and with New York Heart Association (NYHA) class III symptoms, eight months after myectomy and refractory to medical treatment. Cardiac transplantation was indicated due to the severity of symptoms. But the lymphocyte reaction test showed almost 100% reaction of antibodies, and the surgeons rejected the heart transplantation for fear of hyperacute rejection. Then an alcohol septal ablation (ASA) was proposed, which was successfully performed on August 17, 2005. The post-extrasystolic gradient was reduced from 160 to 60 mm Hg immediately and no other complications were seen. The child is being followed since then and echocardiography changes include a further reduction of septum thickness and gradient (P = 0.001), and important symptoms relieved after 3.5 years of follow up. ASA may be an option to be considered in children with critical hypertrophic obstructive cardiomyopathy in NYHA functional class III/IV, when other methods of treatment failed. (c) 2010 Wiley-Liss, Inc. FAU - Cano, Manuel Nicolas AU - Cano MN AD - Interventional Cardiology Department, Hospital do Coracao, Associacao do Sanatorio Sirio, Sao Paulo, Brazil. sjcano@terra.com.br FAU - Fortunato de Cano, Silvia Judith AU - Fortunato de Cano SJ FAU - Sousa, J Eduardo M R AU - Sousa JE LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Catheter Cardiovasc Interv JT - Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions JID - 100884139 RN - 3K9958V90M (Ethanol) SB - IM CIN - Catheter Cardiovasc Interv. 2010 Nov 1;76(5):724-5. PMID: 20976754 MH - *Ablation Techniques MH - *Cardiac Surgical Procedures MH - Cardiomyopathy, Hypertrophic/diagnostic imaging/physiopathology/surgery/*therapy MH - Child MH - Contraindications MH - Echocardiography, Doppler, Color MH - Electrocardiography MH - Ethanol/*administration & dosage MH - Heart Failure/diagnostic imaging/physiopathology/surgery/*therapy MH - Heart Transplantation MH - Humans MH - Male MH - Recovery of Function MH - Severity of Illness Index MH - Treatment Failure MH - Ventricular Function EDAT- 2010/08/28 06:00 MHDA- 2011/02/10 06:00 CRDT- 2010/08/28 06:00 PHST- 2010/08/28 06:00 [entrez] PHST- 2010/08/28 06:00 [pubmed] PHST- 2011/02/10 06:00 [medline] AID - 10.1002/ccd.22539 [doi] PST - ppublish SO - Catheter Cardiovasc Interv. 2010 Nov 1;76(5):719-23. doi: 10.1002/ccd.22539.