PMID- 20803045
OWN - NLM
STAT- MEDLINE
DCOM- 20110104
LR  - 20220409
IS  - 1434-9949 (Electronic)
IS  - 0770-3198 (Linking)
VI  - 29
IP  - 11
DP  - 2010 Nov
TI  - Assessment of fatigue in Moroccan patients with ankylosing spondylitis.
PG  - 1295-9
LID - 10.1007/s10067-010-1558-4 [doi]
AB  - This study aims to assess fatigue aspects in Moroccan patients with ankylosing 
      spondylitis (AS), and its relationships with disease-specific variables of 
      activity and severity. A cross-sectional study included patients with ankylosing 
      spondylitis according to New York Classification criteria for the diagnosis of 
      AS. To assess fatigue, the first item of Bath Ankylosing Spondylitis Disease 
      Activity index (BASDAI) and the Multidimensional assessment of fatigue were used 
      (MAF). The evaluation included the activity of the disease (BASDAI), global 
      well-being (Bath Ankylosing Spondylitis Global Index), functional status (Bath 
      Ankylosing Spondylitis Functional Index), enthesitis and health-related quality 
      of life (SF-36 generic instrument). One hundred patients were included (67 men 
      and 33 women), of average age 38.0 years +/- 12.9 [18-72]. Our patients had a 
      moderately active and a severe disease. In our data, 60% experienced severe 
      fatigue (BASDAI fatigue >/= 50 mm) and mean total score of MAF = 32.0 +/- 20. Gender, 
      NSAID therapy and the presence of biological inflammatory syndrome did not 
      influence the MAF scores. Higher scores of fatigue were correlated with 
      functional disability, general well-being, disease activity, enthesitis, and the 
      deterioration of five domains of SF-36. Multivariate regression showed strong 
      relationship between fatigue severity and general well-being and enthesitis. 
      Severe fatigue (MAF) was most related with the domain of physical function. This 
      study state the importance of fatigue in AS patients. The severity of fatigue is 
      associated with disease activity, functional disability, general well-being, and 
      enthesitis. Fatigue influences negatively different aspects of quality of life. 
      Fatigue is an important outcome measure that must be part of routine clinical 
      evaluation of our AS patients.
FAU - Ibn Yacoub, Yousra
AU  - Ibn Yacoub Y
AD  - Department of Rheumatology, El Ayachi Hospital, University Hospital of 
      Rabat-Sale, 11000, Sale, Morocco. yiy2005@hotmail.com
FAU - Amine, Bouchra
AU  - Amine B
FAU - Laatiris, Assia
AU  - Laatiris A
FAU - Abouqal, Redouane
AU  - Abouqal R
FAU - Hajjaj-Hassouni, Najia
AU  - Hajjaj-Hassouni N
LA  - eng
PT  - Journal Article
DEP - 20100828
PL  - Germany
TA  - Clin Rheumatol
JT  - Clinical rheumatology
JID - 8211469
SB  - IM
MH  - Activities of Daily Living
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Cross-Sectional Studies
MH  - Disability Evaluation
MH  - Fatigue/*complications/epidemiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Morocco
MH  - Severity of Illness Index
MH  - Spondylitis, Ankylosing/*complications/epidemiology
MH  - Surveys and Questionnaires
EDAT- 2010/08/31 06:00
MHDA- 2011/01/05 06:00
CRDT- 2010/08/31 06:00
PHST- 2010/02/08 00:00 [received]
PHST- 2010/08/13 00:00 [accepted]
PHST- 2010/08/07 00:00 [revised]
PHST- 2010/08/31 06:00 [entrez]
PHST- 2010/08/31 06:00 [pubmed]
PHST- 2011/01/05 06:00 [medline]
AID - 10.1007/s10067-010-1558-4 [doi]
PST - ppublish
SO  - Clin Rheumatol. 2010 Nov;29(11):1295-9. doi: 10.1007/s10067-010-1558-4. Epub 2010 
      Aug 28.