PMID- 20817436
OWN - NLM
STAT- MEDLINE
DCOM- 20111128
LR  - 20110802
IS  - 1873-4022 (Electronic)
IS  - 1873-4022 (Linking)
VI  - 36
IP  - 3
DP  - 2011 Autumn
TI  - Dosimetric comparison of manual and beam angle optimization of gantry angles in 
      IMRT.
PG  - 313-6
LID - 10.1016/j.meddos.2010.07.001 [doi]
AB  - Dosimetric comparison of manual beam angle selection (MBS) and beam angle 
      optimization (BAO) for IMRT plans is investigated retrospectively for 15 head and 
      neck and prostate patients. The head and neck and prostate had planning target 
      volumes (PTVs) ranging between 96.0 and 319.9 cm(3) and 153.6 and 321.3 cm(3), 
      whereas OAR ranged between 8.3 and 47.8 cm(3) and 68.3 and 469.2 cm(3), 
      respectively. In MBS, a standard coplanar 7-9 fields equally spaced gantry angles 
      were used. In BAO, the selection of gantry angle was optimized by the algorithm 
      for the same number of beams. The optimization and dose-volume constraints were 
      kept the same for both techniques. Treatment planning was performed on the 
      Eclipse treatment planning system. Our results showed that the dose-volume 
      histogram for PTV are nearly identical in both techniques but BAO provided 
      superior sparing of the organs at risk compared with the MBS. Also, MBS produced 
      statistically significant higher monitor units (MU) and segments than the BAO; 
      13.1 +/- 6.6% (p = 0.012) and 10.4 +/- 13.6% (p = 0.140), and 14.6 +/- 5.6% (p = 
      1.003E-5) and 12.6 +/- 7.4% (p = 0.76E-3) for head and neck and prostate cases, 
      respectively. The reduction in MU translates into the reduction in total body and 
      integral dose. It is concluded that BAO provides advantage over MBS for most 
      intenisty-modulated radiation therapy cases.
CI  - Copyright (c) 2011 American Association of Medical Dosimetrists. Published by 
      Elsevier Inc. All rights reserved.
FAU - Srivastava, Shiv P
AU  - Srivastava SP
AD  - Department of Radiation Oncology, Reid Hospital & Health Care Services, Richmond, 
      IN 46202, USA.
FAU - Das, Indra J
AU  - Das IJ
FAU - Kumar, Arvind
AU  - Kumar A
FAU - Johnstone, Peter A S
AU  - Johnstone PA
LA  - eng
PT  - Comparative Study
PT  - Journal Article
DEP - 20100903
PL  - United States
TA  - Med Dosim
JT  - Medical dosimetry : official journal of the American Association of Medical 
      Dosimetrists
JID - 8908862
SB  - IM
MH  - Head and Neck Neoplasms/*radiotherapy
MH  - Humans
MH  - Male
MH  - Prostatic Neoplasms/*radiotherapy
MH  - Radiotherapy Dosage
MH  - Radiotherapy Planning, Computer-Assisted/*methods
MH  - Radiotherapy, Intensity-Modulated/*methods
MH  - Retrospective Studies
EDAT- 2010/09/08 06:00
MHDA- 2011/12/13 00:00
CRDT- 2010/09/07 06:00
PHST- 2010/02/11 00:00 [received]
PHST- 2010/06/30 00:00 [revised]
PHST- 2010/07/11 00:00 [accepted]
PHST- 2010/09/07 06:00 [entrez]
PHST- 2010/09/08 06:00 [pubmed]
PHST- 2011/12/13 00:00 [medline]
AID - S0958-3947(10)00113-5 [pii]
AID - 10.1016/j.meddos.2010.07.001 [doi]
PST - ppublish
SO  - Med Dosim. 2011 Autumn;36(3):313-6. doi: 10.1016/j.meddos.2010.07.001. Epub 2010 
      Sep 3.