PMID- 2081820
OWN - NLM
STAT- MEDLINE
DCOM- 19910507
LR  - 20061115
IS  - 0021-9967 (Print)
IS  - 0021-9967 (Linking)
VI  - 302
IP  - 4
DP  - 1990 Dec 22
TI  - Comparative distribution of neuropeptide-immunoreactive systems in the brain of 
      the green molly, Poecilia latipinna.
PG  - 893-919
AB  - The comparative distribution of peptidergic neural systems in the brain of the 
      euryhaline, viviparous teleost Poecilia latipinna (green molly) was examined by 
      immunohistochemistry. Topographically distinct, but often overlapping, systems of 
      neurons and fibres displaying immunoreactivity (ir) related to a range of 
      neuropeptides were found in most brain areas. Neurosecretory and 
      hypophysiotrophic hormones were localized to specific groups of neurons mostly 
      within the preoptic and tuberal hypothalamus, giving fibre projections to the 
      neurohypophysis, ventral telencephalon, thalamus, and brain stem. Separate 
      vasotocin (AVT)-ir and isotocin (IST)-ir cells were located in the nucleus 
      preopticus (nPO), but many AVT-ir nPO neurons also displayed growth 
      hormone-releasing factor (GRF)-like-ir, and in some animals 
      corticotrophin-releasing factor (CRF)-like-ir. The main group of CRF-ir neurons 
      was located in the nucleus recessus anterioris, where coexistence with galanin 
      (GAL) was observed in some cells. Enkephalin (ENK)-like-ir was occasionally 
      present in a few IST-ir cells of the nPO and was also found in small neurons in 
      the posterior tuberal hypothalamus and in a cluster of large cells in the dorsal 
      midbrain tegmentum. Thyrotrophin-releasing hormone (TRH)-ir cells were found near 
      the rostromedial tip of the nucleus recessus lateralis. Gonadotrophin-releasing 
      hormone (GnRH)-ir cells were present in the nucleus olfactoretinalis, ventral 
      telencephalon, preoptic area, and dorsal midbrain tegmentum. Molluscan 
      cardioexcitatory peptide (FMRF-amide)-ir was colocalized with GnRH-ir in the 
      ganglion cells and central projections of the nervus terminalis. 
      Melanin-concentrating hormone (MCH)-ir neurons were restricted to the tuberal 
      hypothalamus, mostly within the nucleus lateralis tuberis pars lateralis, and 
      somatostatin (SRIF)-ir neurons were numerous throughout the periventricular areas 
      of the diencephalon. A further group of SRIF-ir neurons extending from the 
      ventral telencephalon into the dorsal telencephalon pars centralis also contained 
      neuropeptide Y (NPY)-, peptide YY (PYY)-, and NPY flanking peptide (PSW)-like-ir. 
      These immunoreactivities were, however, also observed in non-SRIF-ir cells and 
      fibres, particularly in the mesencephalon. Calcitonin gene-related peptide 
      (CGRP)-like-ir had a characteristic distribution in cells grouped in the isthmal 
      region and fibre tracts running forward into the hypothalamus, most strikingly 
      into the inferior lobes. Antisera to cholecystokinin (CCK) and neurokinin A (NK) 
      or substance P (SP) stained very extensive, separate systems throughout the 
      brain, with cells most consistently seen in the ventral telencephalon and 
      periventricular hypothalamus. Broadly similar, but much more restricted, 
      distributions of cells and fibres were seen with antisera to neurotensin (NT) and 
      vasoactive intestinal peptide (VIP).(ABSTRACT TRUNCATED AT 400 WORDS)
FAU - Batten, T F
AU  - Batten TF
AD  - Department of Cardiovascular Studies, University Leeds, England.
FAU - Cambre, M L
AU  - Cambre ML
FAU - Moons, L
AU  - Moons L
FAU - Vandesande, F
AU  - Vandesande F
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Comp Neurol
JT  - The Journal of comparative neurology
JID - 0406041
RN  - 0 (Immune Sera)
RN  - 0 (Neuropeptides)
SB  - IM
MH  - Animals
MH  - Brain/*anatomy & histology
MH  - *Brain Chemistry
MH  - Female
MH  - Immune Sera
MH  - Immunoenzyme Techniques
MH  - Male
MH  - Neuropeptides/*analysis
MH  - Neurosecretory Systems/anatomy & histology/chemistry
MH  - Poecilia/*anatomy & histology
EDAT- 1990/12/22 00:00
MHDA- 1990/12/22 00:01
CRDT- 1990/12/22 00:00
PHST- 1990/12/22 00:00 [pubmed]
PHST- 1990/12/22 00:01 [medline]
PHST- 1990/12/22 00:00 [entrez]
AID - 10.1002/cne.903020416 [doi]
PST - ppublish
SO  - J Comp Neurol. 1990 Dec 22;302(4):893-919. doi: 10.1002/cne.903020416.