PMID- 20819472
OWN - NLM
STAT- MEDLINE
DCOM- 20110315
LR  - 20111110
IS  - 1945-8932 (Electronic)
IS  - 1945-8932 (Linking)
VI  - 24
IP  - 4
DP  - 2010 Jul-Aug
TI  - Restoration of nasal cytology after endoscopic turbinoplasty versus 
      laser-assisted turbinoplasty.
PG  - 310-4
LID - 10.2500/ajra.2010.24.3474 [doi]
AB  - BACKGROUND: Insult from surgical trauma leads to a degeneration of the nasal 
      epithelium, resulting in morphological-volumetric changes involving the entire 
      cell or a specific cell component. Alterations in normal nasal mucosa were 
      assessed by nasal cytology and other functional tests after either endoscopic 
      turbinoplasty or laser-assisted turbinoplasty for reducing inferior turbinate 
      enlargement. METHODS: A total of 150 patients with chronic nasal obstruction due 
      to inferior turbinate hypertrophy were randomly assigned to undergo 
      laser-assisted turbinoplasty or endoscopic turbinoplasty. Preoperative and 
      postoperative assessment at 1 and 3 months follow-up included active anterior 
      rhinomanometry, measurement of mucociliary transport time (MCTt), and nasal 
      cytology to determine whether improved nasal breathing was accompanied by a 
      restoration of preoperative nasal cytology and MCTt. One year after the 
      operation, nasal cytology was repeated to definitively evaluate the presence of 
      surgery-related cytological damage. RESULTS: At both postoperative visits, nasal 
      resistance had decreased similarly in both treatment groups; mean MCTt was 
      significantly shorter in the endoscopic turbinoplasty-treated group (p < 0.05); 
      at both visits, the number of altered ciliated cells had increased in the 
      laser-assisted turbinoplasty-treated group but decreased in the endoscopic 
      turbinoplasty-treated group, which, unlike the laser-assisted 
      turbinoplasty-treated group, was also noted to have progressed toward a 
      significant improvement in the goblet-to-ciliated cell ratio (p < 0.01). 
      CONCLUSION: When compared with laser-assisted turbinoplasty, endoscopic 
      turbinoplasty is a conservative technique for inferior turbinate reduction that 
      allows better restoration of preoperative nasal cytology and shorter MCTt.
FAU - Cassano, Michele
AU  - Cassano M
AD  - Department of Otorhinolaryngology, University of Foggia, Foggia, Italy. 
      m.cassano@unifg.it
FAU - Granieri, Carla
AU  - Granieri C
FAU - Del Giudice, Alessandro Maselli
AU  - Del Giudice AM
FAU - Mora, Francesco
AU  - Mora F
FAU - Fiocca-Matthews, Emily
AU  - Fiocca-Matthews E
FAU - Cassano, Pasquale
AU  - Cassano P
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Am J Rhinol Allergy
JT  - American journal of rhinology & allergy
JID - 101490775
SB  - IM
MH  - Adult
MH  - Aged
MH  - Breath Tests
MH  - Cell Death
MH  - Endoscopy/*adverse effects
MH  - Female
MH  - Follow-Up Studies
MH  - Goblet Cells/pathology
MH  - Humans
MH  - Hypertrophy/diagnosis/pathology/*therapy
MH  - Laser Therapy/*adverse effects
MH  - Male
MH  - Middle Aged
MH  - Mucociliary Clearance
MH  - Nasal Mucosa/injuries/*pathology/surgery
MH  - Rhinomanometry
MH  - Surgical Wound Dehiscence/*etiology/prevention & control
MH  - Turbinates/pathology/*surgery
EDAT- 2010/09/08 06:00
MHDA- 2011/03/16 06:00
CRDT- 2010/09/08 06:00
PHST- 2010/09/08 06:00 [entrez]
PHST- 2010/09/08 06:00 [pubmed]
PHST- 2011/03/16 06:00 [medline]
AID - 10.2500/ajra.2010.24.3474 [doi]
PST - ppublish
SO  - Am J Rhinol Allergy. 2010 Jul-Aug;24(4):310-4. doi: 10.2500/ajra.2010.24.3474.