PMID- 20837072 OWN - NLM STAT- MEDLINE DCOM- 20110225 LR - 20101124 IS - 1872-7492 (Electronic) IS - 0168-1702 (Linking) VI - 154 IP - 1-2 DP - 2010 Dec TI - Molecular epidemiology of PRRSV: a phylogenetic perspective. PG - 7-17 LID - 10.1016/j.virusres.2010.08.014 [doi] AB - Since its first discovery two decades ago, porcine reproductive and respiratory syndrome virus (PRRSV) has been the subject of intensive research due to its huge impact on the worldwide swine industry. Thanks to the phylogenetic analyses, much has been learned concerning the genetic diversity and evolution history of the virus. In this review, we focused on the evolutionary and epidemiological aspects of PRRSV from a phylogenetic perspective. We first described the diversity and transmission dynamics of Type 1 and 2 PRRSV, respectively. Then, we focused on the more ancient evolutionary history of PRRSV: the time of onset of all existing PRRSV and an origin hypothesis were discussed. Finally, we summarized the results from previous recombination studies to assess the potential impact of recombination on the virus epidemiology. CI - Copyright (c) 2010 Elsevier B.V. All rights reserved. FAU - Shi, Mang AU - Shi M AD - School of Biological Sciences, The University of Hong Kong, Hong Kong, China. FAU - Lam, Tommy Tsan-Yuk AU - Lam TT FAU - Hon, Chung-Chau AU - Hon CC FAU - Hui, Raymond Kin-Hei AU - Hui RK FAU - Faaberg, Kay S AU - Faaberg KS FAU - Wennblom, Trevor AU - Wennblom T FAU - Murtaugh, Michael P AU - Murtaugh MP FAU - Stadejek, Tomasz AU - Stadejek T FAU - Leung, Frederick Chi-Ching AU - Leung FC LA - eng PT - Journal Article PT - Review DEP - 20100915 PL - Netherlands TA - Virus Res JT - Virus research JID - 8410979 RN - 0 (RNA, Viral) SB - IM MH - Animals MH - Cluster Analysis MH - Evolution, Molecular MH - Genetic Variation MH - Molecular Epidemiology MH - Porcine Reproductive and Respiratory Syndrome/*epidemiology/transmission/*virology MH - Porcine respiratory and reproductive syndrome virus/*classification/genetics/*isolation & purification MH - RNA, Viral/genetics MH - Recombination, Genetic MH - Swine EDAT- 2010/09/15 06:00 MHDA- 2011/02/26 06:00 CRDT- 2010/09/15 06:00 PHST- 2010/05/17 00:00 [received] PHST- 2010/08/11 00:00 [revised] PHST- 2010/08/16 00:00 [accepted] PHST- 2010/09/15 06:00 [entrez] PHST- 2010/09/15 06:00 [pubmed] PHST- 2011/02/26 06:00 [medline] AID - S0168-1702(10)00291-1 [pii] AID - 10.1016/j.virusres.2010.08.014 [doi] PST - ppublish SO - Virus Res. 2010 Dec;154(1-2):7-17. doi: 10.1016/j.virusres.2010.08.014. Epub 2010 Sep 15.