PMID- 20839456
OWN - NLM
STAT- MEDLINE
DCOM- 20101022
LR  - 20100915
IS  - 0035-7715 (Print)
IS  - 0035-7715 (Linking)
VI  - 61
IP  - 2
DP  - 2010
TI  - [Organohalogen compounds--new and old hazards for people].
PG  - 109-17
AB  - The organohalogen compounds (OCs, PCBs, PBDEs) are persistent organic pollutants 
      (POPs) that have a widespread distribution in the environment. Their 
      chemico-physical stability and lipophylic properties are responsible for their 
      accumulation in the human body. The general human population is exposed to PCBs 
      and OCs through foodstuffs, mainly food of animal origin. However the main source 
      of the human exposure to PBDEs are also food and inhalation of dust or respirable 
      phase of the indoor air The POPs from this group are present on different levels 
      in human tissues (fat tissue, liver; placenta), and even in human blood and 
      breast milk. The organohalogen compounds may cause endocrine disrupting (ED) 
      effects as they have been shown to interact as antagonists or agonists with 
      androgen, progesterone, and estrogen receptors. Most of them shows 
      antiandrogenic, estrogenic and antiestrogenic activity.
FAU - Goralczyk, Katarzyna
AU  - Goralczyk K
AD  - Zaklad Toksykologii Srodowiskowej, Narodowy Instytut Zdrowia 
      Publicznego-Panstwowy Zaklad Higieny, Warszawa. kgoralczyk@pzh.gov.pl
FAU - Hernik, Agnieszka
AU  - Hernik A
FAU - Czaja, Katarzyna
AU  - Czaja K
FAU - Strucinski, Pawel
AU  - Strucinski P
FAU - Korcz, Wojciech
AU  - Korcz W
FAU - Snopczynski, Tomasz
AU  - Snopczynski T
FAU - Ludwicki, Jan K
AU  - Ludwicki JK
LA  - pol
PT  - English Abstract
PT  - Journal Article
TT  - Zwiazki halogenorganiczne --stare i nowe zagrozenia].
PL  - Poland
TA  - Rocz Panstw Zakl Hig
JT  - Roczniki Panstwowego Zakladu Higieny
JID - 0414756
RN  - 0 (Carcinogens, Environmental)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Halogenated)
SB  - IM
MH  - Carcinogens, Environmental/metabolism
MH  - Environmental Exposure/*statistics & numerical data
MH  - Environmental Pollutants/*metabolism/*toxicity
MH  - Food Contamination/*statistics & numerical data
MH  - Humans
MH  - Hydrocarbons, Halogenated/*metabolism/*toxicity
MH  - Kidney/metabolism
MH  - Liver/metabolism
MH  - Risk Factors
EDAT- 2010/09/16 06:00
MHDA- 2010/10/23 06:00
CRDT- 2010/09/16 06:00
PHST- 2010/09/16 06:00 [entrez]
PHST- 2010/09/16 06:00 [pubmed]
PHST- 2010/10/23 06:00 [medline]
PST - ppublish
SO  - Rocz Panstw Zakl Hig. 2010;61(2):109-17.