PMID- 20840248
OWN - NLM
STAT- MEDLINE
DCOM- 20100928
LR  - 20181201
IS  - 1749-6632 (Electronic)
IS  - 0077-8923 (Linking)
VI  - 1205
DP  - 2010 Sep
TI  - Umbilical cord blood stem cells: what to expect.
PG  - 17-22
LID - 10.1111/j.1749-6632.2010.05659.x [doi]
AB  - Umbilical cord blood (UCB) is a valuable alternative source of hematopoietic stem 
      cells (HSCs). It has unique advantages of easy procurement, absence of risk to 
      donors, low risk of transmitting infections, immediate availability, greater 
      tolerance of human leukocyte antigen (HLA) disparity, and lower incidence of 
      inducing severe graft-versus-host disease (GVHD). In the last several years, 
      these features of UCB permit the field of UCB transplantation (UCBT) to move at a 
      faster pace for both children and adults with malignancies and nonmalignancies. 
      However, new strategies and novel developments are expected to improve 
      engraftment and reconstitution, and to enable in utero transplantation for early 
      therapy, as well as to allow the therapy for a wide spectrum of human diseases.
CI  - (c) 2010 New York Academy of Sciences.
FAU - Zhong, Xiao Yan
AU  - Zhong XY
AD  - Laboratory for Gynecologic Oncology, Women's Hospital/Department of Biomedicine, 
      University of Basel, Switzerland. xzhong@uhbs.ch
FAU - Zhang, Bei
AU  - Zhang B
FAU - Asadollahi, Reza
AU  - Asadollahi R
FAU - Low, Shyan Huey
AU  - Low SH
FAU - Holzgreve, Wolfgang
AU  - Holzgreve W
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - United States
TA  - Ann N Y Acad Sci
JT  - Annals of the New York Academy of Sciences
JID - 7506858
SB  - IM
MH  - Adult
MH  - Animals
MH  - Cord Blood Stem Cell Transplantation/methods/statistics & numerical data/*trends
MH  - Fetal Blood/*cytology/physiology
MH  - Hematologic Neoplasms/therapy
MH  - Hematopoietic Stem Cells/*physiology
MH  - Humans
MH  - Immunologic Deficiency Syndromes/therapy
MH  - Metabolic Diseases/therapy
RF  - 40
EDAT- 2010/09/16 06:00
MHDA- 2010/09/30 06:00
CRDT- 2010/09/16 06:00
PHST- 2010/09/16 06:00 [entrez]
PHST- 2010/09/16 06:00 [pubmed]
PHST- 2010/09/30 06:00 [medline]
AID - 10.1111/j.1749-6632.2010.05659.x [doi]
PST - ppublish
SO  - Ann N Y Acad Sci. 2010 Sep;1205:17-22. doi: 10.1111/j.1749-6632.2010.05659.x.