PMID- 20842699
OWN - NLM
STAT- MEDLINE
DCOM- 20110428
LR  - 20151119
IS  - 1099-0801 (Electronic)
IS  - 0269-3879 (Linking)
VI  - 25
IP  - 1-2
DP  - 2011 Jan
TI  - Simultaneous determination of three acidic herbicide residues in food crops using 
      HPLC and confirmation via LC-MS/MS.
PG  - 124-35
LID - 10.1002/bmc.1513 [doi]
AB  - 2,4-D, dicamba and 4-CPA with auxin-like activity have been intensively used in 
      agriculture, for the control of unwanted broadleaf weeds. An analytical method 
      involving HPLC coupled with UVD was developed for the simultaneous analysis of 
      these three analytes in Chinese cabbage, apple and pepper fruits (representative 
      non-fatty samples) and brown rice and soybean (representative fatty samples) 
      using liquid-liquid partitioning and column cleanup procedures. The residues were 
      confirmed via tandem mass spectrometry (MS/MS) in ion electrospray ionization 
      (ESI) mode. The standard curves were linear over the range of the tested 
      concentrations (0.25-10 microg/mL), as shown by a marked linearity in excess of 
      0.9999 (r(2) ). The average recoveries (mean, n = 3) ranged from 94.30 to 102.63 
      in Chinese cabbage, from 94.76 to 108.47 in apple, from 97.52 to 102.27 in 
      pepper, from 76.19 to 101.90 in brown rice, and from 74.60 to 107.39 in soybean. 
      The relative standard deviations (RSDs) were <9% in all tested matrices. The 
      limits of detection and quantitation were 0.006 and 0.02 mg/kg, respectively. 
      Samples purchased from local markets were analyzed to evaluate the applicability 
      of the methods developed herein. The concentration of the 2,4-D residue was 
      measured at 0.102 mg/kg in the soybean sample; however, this level is exactly the 
      same MRL set by the Korea Food and Drug Administration. This developed method 
      deserves full and complete consideration, as it clearly displays the sensitivity, 
      accuracy and precision required for residue analysis of 2,4-D, dicamba and 4-CPA 
      in food crops.
CI  - 2010 John Wiley & Sons, Ltd.
FAU - Shin, Eun-Ho
AU  - Shin EH
AD  - Natural Products Chemistry Laboratory, College of Agriculture and Life Science, 
      Chonnam National University, 77 Yongbong-ro, Buk-gu, Gwangju 500-757, Republic of 
      Korea.
FAU - Choi, Jeong-Heui
AU  - Choi JH
FAU - Abd El-Aty, A M
AU  - Abd El-Aty AM
FAU - Khay, Sathya
AU  - Khay S
FAU - Kim, Sun-Ju
AU  - Kim SJ
FAU - Im, Moo Hyeog
AU  - Im MH
FAU - Kwon, Chan-Hyeok
AU  - Kwon CH
FAU - Shim, Jae-Han
AU  - Shim JH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20100914
PL  - England
TA  - Biomed Chromatogr
JT  - Biomedical chromatography : BMC
JID - 8610241
RN  - 0 (Pesticide Residues)
RN  - 2577AQ9262 (2,4-Dichlorophenoxyacetic Acid)
RN  - SJG3M6RY6H (Dicamba)
SB  - IM
MH  - 2,4-Dichlorophenoxyacetic Acid/analogs & derivatives/*analysis/chemistry
MH  - Chromatography, High Pressure Liquid/*methods
MH  - Dicamba/*analysis/chemistry
MH  - Food Analysis/*methods
MH  - Fruit/chemistry
MH  - Linear Models
MH  - Oryza/chemistry
MH  - Pesticide Residues/*analysis/chemistry
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Tandem Mass Spectrometry/*methods
EDAT- 2010/09/16 06:00
MHDA- 2011/04/29 06:00
CRDT- 2010/09/16 06:00
PHST- 2010/07/19 00:00 [received]
PHST- 2010/07/26 00:00 [accepted]
PHST- 2010/09/16 06:00 [entrez]
PHST- 2010/09/16 06:00 [pubmed]
PHST- 2011/04/29 06:00 [medline]
AID - 10.1002/bmc.1513 [doi]
PST - ppublish
SO  - Biomed Chromatogr. 2011 Jan;25(1-2):124-35. doi: 10.1002/bmc.1513. Epub 2010 Sep 
      14.