PMID- 20848930 OWN - NLM STAT- MEDLINE DCOM- 20141108 LR - 20100920 IS - 1000-1182 (Print) IS - 1000-1182 (Linking) VI - 28 IP - 4 DP - 2010 Aug TI - [Relationship between periodontitis and levels of high-sensitivity C-reactive protein]. PG - 382-6 AB - OBJECTIVE: To evaluate the relationship between periodontitis and the traditional risk factors of coronary heart disease (CHD), as well as the role in the mechanisms responsible for high-sensitivity C-reactive protein (hsCRP) in the relationship of peridontitis and CHD. METHODS: A periodontal examination was conducted on a total of 356 subjects, and community periodontal index of treatment needs (CPITN) was obtained from each subject. Periodontal status was categorized into TN < or =2, TN=3, TN=4 three groups according to the CPITN indexes. Fasting venous blood samples were collected from all the three group subjects, the serum hsCRP concentration and serological changes used in diagnosing CHD routinely were determined, and software of SPSS 16.0 were used to analyzed the relationship of periodontal, hsCRP concentration and routinely CHD serological indexes. RESULTS: In the groups of TN < or =2, TN=3 and TN=4, the hsCRP level was (1.10 +/- 1.16), (1.86 +/- 2.34), (2.25 +/- 2.75) mg x L(-1), respectively. Compared with Group TN < or =2, the concentration of hsCRP in Group TN=3 and TN=4 were higher (OR = 1.24, OR = 1.31, respectively). Compared with group hsCRP < 3.0 mg x L(-1), more calculus and deep periodontal pockets were found in the Group hsCRP > or = 3.0 mg x L(-1) (P < 0.05). CONCLUSION: The serum hsCRP level is correlated with the severity of periodontal disease. FAU - Pan, Heng-biao AU - Pan HB AD - Dept. of Oral Medicine, Stomatology Hospital, College of Medicine, Zhejiang University, Hangzhou 310006, China. FAU - Chen, Hui AU - Chen H FAU - Zhou, Na AU - Zhou N FAU - Jin, Dan AU - Jin D FAU - Zhang, Jing AU - Zhang J FAU - Peng, Chun-mei AU - Peng CM LA - chi PT - English Abstract PT - Journal Article PL - China TA - Hua Xi Kou Qiang Yi Xue Za Zhi JT - Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology JID - 9422648 RN - 9007-41-4 (C-Reactive Protein) SB - IM MH - C-Reactive Protein/*chemistry MH - Coronary Disease MH - Humans MH - Periodontal Index MH - Periodontitis/blood/*diagnosis MH - Risk Factors EDAT- 2010/09/21 06:00 MHDA- 2014/11/09 06:00 CRDT- 2010/09/21 06:00 PHST- 2010/09/21 06:00 [entrez] PHST- 2010/09/21 06:00 [pubmed] PHST- 2014/11/09 06:00 [medline] PST - ppublish SO - Hua Xi Kou Qiang Yi Xue Za Zhi. 2010 Aug;28(4):382-6.