PMID- 20859886
OWN - NLM
STAT- MEDLINE
DCOM- 20101207
LR  - 20181201
IS  - 0022-9032 (Print)
IS  - 0022-9032 (Linking)
VI  - 68
IP  - 9
DP  - 2010 Sep
TI  - Risk factors of asymptomatic restenosis in patients with first anterior ST 
      elevation myocardial infarction treated by primary percutaneous coronary 
      intervention.
PG  - 987-93
AB  - BACKGROUND: The issue of predicting coronary artery restenosis, especially 
      silent, in patients following primary percutaneous coronary intervention (PCI) 
      has been extensively studied, however, risk factors have not been fully defined. 
      AIM: To asses the frequency of silent restenosis and its predictors in patients 
      with anterior ST elevation myocardial infarction (STEMI) treated with primary PCI 
      and implantation of bare metal stents (BMS). METHODS: We recruited a cohort of 
      114 patients with first anterior STEMI treated with primary PCI within 12 hours 
      of the onset of symptoms, and with the left anterior descending coronary artery 
      occlusion (TIMI 0) and successful flow restoration (TIMI 3). A 12-lead ECG was 
      performed before and 60 minutes after PCI. Troponin I and CK-MB were measured on 
      admission and after six, 12 and 24 hours. Transthoracic echocardiography (TTE) 
      was performed at discharge. Resting TTE and coronary angiography were performed 
      after a six month follow-up in asymptomatic patients. RESULTS: The frequency of 
      silent restenosis in our study group was 23.9%. The best multivariate models in 
      logistic regression of restenosis prediction were: lower end-systolic volume of 
      the left ventricle assessed two days after infarction longer lesion and smaller 
      reference diameter of the stented vessel. CONCLUSIONS: Silent restenosis in 
      patients with first anterior STEMI treated by primary PCI with the use of BMS is 
      still frequent. The best ways to identify patients with silent restenosis at six 
      month follow-up, apart from the lower end systolic volume in the 
      echocardiographic study, are longer narrowing in the infarct-related artery and 
      lower reference diameter of the treated vessel.
FAU - Wita, Krystian
AU  - Wita K
AD  - 1st Department of Cardiology, Upper Silesian Medical Centre, SPSK 7, Katowice, 
      Poland.
FAU - Kinasz, Leszek
AU  - Kinasz L
FAU - Filipecki, Artur
AU  - Filipecki A
FAU - Lelek, Michal
AU  - Lelek M
FAU - Szczogiel, Jan
AU  - Szczogiel J
FAU - Turski, Maciej
AU  - Turski M
FAU - Weglarz, Przemyslaw
AU  - Weglarz P
FAU - Elzbieciak, Marek
AU  - Elzbieciak M
FAU - Staron, Adam
AU  - Staron A
FAU - Trusz-Gluza, Maria
AU  - Trusz-Gluza M
LA  - eng
PT  - Journal Article
PL  - Poland
TA  - Kardiol Pol
JT  - Kardiologia polska
JID - 0376352
SB  - IM
CIN - Kardiol Pol. 2010 Sep;68(9):994-5. PMID: 20859887
MH  - Aged
MH  - Angioplasty, Balloon, Coronary/adverse effects/*statistics & numerical data
MH  - Cohort Studies
MH  - Coronary Restenosis/diagnostic imaging/*epidemiology/etiology
MH  - Echocardiography
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Myocardial Infarction/epidemiology/*therapy
MH  - Poland
MH  - Recurrence
MH  - Regression Analysis
MH  - Risk Factors
MH  - Stents/adverse effects/*statistics & numerical data
EDAT- 2010/09/23 06:00
MHDA- 2010/12/14 06:00
CRDT- 2010/09/23 06:00
PHST- 2010/09/23 06:00 [entrez]
PHST- 2010/09/23 06:00 [pubmed]
PHST- 2010/12/14 06:00 [medline]
PST - ppublish
SO  - Kardiol Pol. 2010 Sep;68(9):987-93.