PMID- 20860817
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20220317
IS  - 1550-2783 (Electronic)
IS  - 1550-2783 (Linking)
VI  - 7
DP  - 2010 Sep 22
TI  - Whey protein isolate attenuates strength decline after eccentrically-induced 
      muscle damage in healthy individuals.
PG  - 30
LID - 10.1186/1550-2783-7-30 [doi]
AB  - BACKGROUND: We examined the effects of short-term consumption of whey protein 
      isolate on muscle proteins and force recovery after eccentrically-induced muscle 
      damage in healthy individuals. METHODS: Seventeen untrained male participants (23 
      +/- 5 yr, 180 +/- 6 cm, 80 +/- 11 kg) were randomly separated into two supplement 
      groups: i) whey protein isolate (WPH; n = 9); or ii) carbohydrate (CHO; n = 8). 
      Participants consumed 1.5 g/kg.bw/day supplement (~30 g consumed immediately, and 
      then once with breakfast, lunch, in the afternoon and after the evening meal) for 
      a period of 14 days following a unilateral eccentric contraction-based resistance 
      exercise session, consisting of 4 sets of 10 repetitions at 120% of maximum 
      voluntary contraction on the leg press, leg extension and leg flexion exercise 
      machine. Plasma creatine kinase and lactate dehydrogenase (LDH) levels were 
      assessed as blood markers of muscle damage. Muscle strength was examined by 
      voluntary isokinetic knee extension using a Cybex dynamometer. Data were analyzed 
      using repeated measures ANOVA with an alpha of 0.05. RESULTS: Isometric knee 
      extension strength was significantly higher following WPH supplementation 3 (P < 
      0.05) and 7 (P < 0.01) days into recovery from exercise-induced muscle damage 
      compared to CHO supplementation. In addition, strong tendencies for higher 
      isokinetic forces (extension and flexion) were observed during the recovery 
      period following WPH supplementation, with knee extension strength being 
      significantly greater (P < 0.05) after 7 days recovery. Plasma LDH levels tended 
      to be lower (P = 0.06) in the WPH supplemented group during recovery. 
      CONCLUSIONS: The major finding of this investigation was that whey protein 
      isolate supplementation attenuated the impairment in isometric and isokinetic 
      muscle forces during recovery from exercise-induced muscle injury.
FAU - Cooke, Matthew B
AU  - Cooke MB
AD  - Exercise Metabolism Unit, Institute for Sport, Exercise and Active Living, School 
      of Biomedical and Health Sciences, Victoria University, Melbourne, Australia.
AD  - Schools of Medicine and Human Movement Studies, Princess Alexandra Hospital, the 
      University of Queensland, Brisbane, Australia.
FAU - Rybalka, Emma
AU  - Rybalka E
AD  - Exercise Metabolism Unit, Institute for Sport, Exercise and Active Living, School 
      of Biomedical and Health Sciences, Victoria University, Melbourne, Australia.
FAU - Stathis, Christos G
AU  - Stathis CG
AD  - Exercise Metabolism Unit, Institute for Sport, Exercise and Active Living, School 
      of Biomedical and Health Sciences, Victoria University, Melbourne, Australia.
FAU - Cribb, Paul J
AU  - Cribb PJ
AD  - Exercise Metabolism Unit, Institute for Sport, Exercise and Active Living, School 
      of Biomedical and Health Sciences, Victoria University, Melbourne, Australia.
FAU - Hayes, Alan
AU  - Hayes A
AD  - Exercise Metabolism Unit, Institute for Sport, Exercise and Active Living, School 
      of Biomedical and Health Sciences, Victoria University, Melbourne, Australia.
LA  - eng
PT  - Journal Article
DEP - 20100922
PL  - United States
TA  - J Int Soc Sports Nutr
JT  - Journal of the International Society of Sports Nutrition
JID - 101234168
PMC - PMC2955583
EDAT- 2010/09/24 06:00
MHDA- 2010/09/24 06:01
PMCR- 2010/09/22
CRDT- 2010/09/24 06:00
PHST- 2010/05/27 00:00 [received]
PHST- 2010/09/22 00:00 [accepted]
PHST- 2010/09/24 06:00 [entrez]
PHST- 2010/09/24 06:00 [pubmed]
PHST- 2010/09/24 06:01 [medline]
PHST- 2010/09/22 00:00 [pmc-release]
AID - 1550-2783-7-30 [pii]
AID - 10.1186/1550-2783-7-30 [doi]
PST - epublish
SO  - J Int Soc Sports Nutr. 2010 Sep 22;7:30. doi: 10.1186/1550-2783-7-30.